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Found 54 clinical trials
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Affecting approximately one-third of the United States (U.S.) population, the prevalence of NAFLD increases to 90% in patients with obesity. In 25% of patients, NAFLD progresses to a more severe form-non-alcoholic steatohepatitis (NASH)-which further increases the risks …

insulin resistance
fibrosis
fatty liver
carcinoma
fasting
  • 0 views
  • 23 May, 2021
  • 1 location
Safety and Efficacy Study of Endovenous Microwave Ablation for Treatment of Varicose Veins (EMINENCE)

The purpose of this study was to evaluate the efficacy and safety of microwave ablation catheter in the treatment of varicose veins in lower extremities,meanwhile, to compare the quality of subjects'lives before and after treatment.

  • 20 views
  • 29 May, 2022
  • 1 location
Targeted Tissue Perfusion Versus Macrocirculatory-guided Standard Care in Patients With Septic Shock (TARTARE-2S)

Background: The recommended monitoring and target levels in septic shock (SSC Guidelines 2012) including mean arterial pressure (MAP) target are not based on robust clinical data. Objective: To test, if in patients with septic shock, tissue perfusion guided (TPG) treatment strategy leads to a faster resolution of hypoperfusion than the …

vasopressin
crystalloid solutions
resuscitation
norepinephrine
vasoconstrictor
  • 7 views
  • 23 Feb, 2022
  • 2 locations
Treatment of Pulmonary Hypertension in High-risk Cardiac Surgery Patients Using Inhalational and Intravenous Agents (levos-milr)

The aim of this study is to examine and compare the effect of Levosimendan and Milrinone administered intravenously and via inhalation respectively in cardiac surgery patients with pulmonary hypertension and right ventricular dysfunction.

levosimendan
anesthesia
hypertension
left ventricular dysfunction
  • 0 views
  • 22 Mar, 2022
  • 1 location
Levosimendan Administration in Pulmonary Hypertension (Levosim-PH)

The aim of the study is to examine the pharmacokinetics and pharmacodynamic properties of Levosimendan in cardiac surgery patients with pulmonary hypertension and impaired right ventricular function.

levosimendan
anesthesia
hypertension
left ventricular dysfunction
  • 0 views
  • 23 Mar, 2022
  • 1 location
Inhaled Anesthetics and Myocardial Strain

Speckle tracking imaging measuring software will be used for offline analysis of transesophageal echocardiogram (TEE) -acquired images of the left ventricle(LV) in four chambers(4C), two chambers (2C) and long axis (LAX) views to calculate global longitudinal strain (GLS) of LV for comparisons between sevoflurane and isoflurane at the same minimum …

  • 0 views
  • 24 May, 2022
  • 1 location
Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance

Glaucoma is a major cause of blindness. The inability to predict a patient's IOP response to medications is a critical barrier for the clinician to consistently provide highly effective IOP-based treatments. Current trial-and-error approaches to glaucoma management are inefficient and have not addressed this barrier as there are no predictive …

intraocular pressure
latanoprost 0.005% eye drops
brimonidine tartrate ophthalmic solution
ophthalmic solution
blindness
  • 0 views
  • 06 May, 2022
  • 3 locations
Acute Post-cardiac Surgery Renal Failure: Prevention Through Individualized Intensive Hemodynamic Management (PrevHemAKI)

BACKGROUND: The incidence of acute kidney injury (AKI) in patients undergoing cardiac surgery can reach 35% and between 2 and 5% require kidney replacement therapy during the AKI episode. The development of AKI n this context is independently associated with higher long-term mortality (5-10 years). In addition, there is strong …

heart surgery
chronic kidney disease
renal injury
replacement therapy
renal failure
  • 0 views
  • 19 Feb, 2022
  • 1 location
Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine

Patients will be randomized the day of surgery upon presentation to the operating room to either a treatment group (PECSII/SAP blocks with bupivacaine HCl plus liposomal bupivacaine) or a control group (PECSII/SAP blocks with bupivacaine HCl plus preservative free normal saline) using secure web-based randomization. Assignments will be based on …

pulmonary resection
lipo
thoracotomy
Accepts healthy volunteers
  • 1 views
  • 25 Mar, 2022
  • 1 location
Effects of TIVA Versus Inhalational Anaesthesia on Circulating Tumour Cells in Hepatocellular Carcinoma Patients

More than 80% of patients with cancer will be exposed to anaesthesia at some point in their treatment. There is increasing evidence that perioperative events, including the type of anaesthesia drugs utilised, have an impact on cancer recurrence and metastases. Although potentially and theoretically curative, surgical resection, manipulation and trauma …

cancer
hepatectomy
carcinoma
metastasis
  • 0 views
  • 08 Oct, 2021
  • 1 location