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Found 54 clinical trials
Hepatic Venous Pressure Gradient-guided Versus Standard Beta-blocker Therapy in Primary Prevention of Variceal Bleeding

Study hypothesis: Hepatic venous pressure gradient (HVPG)-directed primary prophylaxis with nonselective beta-blocker therapy (NSBB) leads to a reduction in first variceal bleeding

varicose veins
cirrhosis
venous pressure
propranolol
hepatic venous pressure gradient
  • 15 views
  • 23 Jan, 2021
  • 5 locations
A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension

aqueous humor (AqH) dynamics (episcleral venous pressure [EVP] and outflow facility) in participants with ocular hypertension (OHT).

screening examination
aqueous humor
ocular hypotensive
ophthalmic solution
brimonidine tartrate ophthalmic solution
  • 0 views
  • 09 Mar, 2022
  • 1 location
Bleeding in Laparoscopic Liver Surgery (MODELS)

blood products transfusion, maintaining conditions of low central venous pressure is considered as standard of care. In animals undergoing laparoscopic hepatectomy, reducing airway pressures represents

  • 0 views
  • 29 Jun, 2022
  • 1 location
Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections (PRICE2)

perioperative morbidity and mortality, as well as possibly long-term oncologic outcome. The purpose of this study is to use whole blood phlebotomy to decrease the central venous pressure, resulting in a state

hepatectomy
intraoperative blood loss
liver surgery
liver resection
phlebotomy
  • 104 views
  • 01 Feb, 2022
  • 3 locations
EUS Guided Portal-systemic Pressure Gradient Measurement

bleeding, ascites, spontaneous bacterial peritonitis, hepatic encephalopathy and mortality. Albeit its clinical significance, direct measurement of portal venous pressure to document portal

hypertension
spontaneous bacterial peritonitis
venous pressure
ascites
encephalopathy
  • 0 views
  • 06 Dec, 2021
  • 1 location
Sildenafil for Liver Fibrosis in Adolescents and Adults After Fontan Operation

carcinoma are increasingly described in patients with Fontan circulation. The Fontan associated liver disease (FALD) is related to the decreased cardiac output and elevated central venous pressure after

liver disease
venous pressure
fibroscan
fibrosis
hepatocellular carcinoma
  • 0 views
  • 14 Jun, 2022
  • 1 location
HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)

patients with hemorrhagic shock and/or liver failure caused by variceal bleeding face a mortality of 5-20%. Hepatic venous pressure gradient (HVPG) is the recommended golden standard for portal

  • 0 views
  • 22 Aug, 2021
  • 4 locations
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement

This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.

liver disease
hypertension
hepatic venous pressure gradient
Accepts healthy volunteers
venous pressure
  • 0 views
  • 13 Dec, 2021
  • 1 location
Efficacy and Safety of Dexmedetomidine in the Analgesic Prophylaxis in Patients Undergoing Cardiovascular Surgery

Acute pain is one of the complications after cardiothoracic surgeries . It can delay patientsrecovery and may increase patientsmorbity and mortality. This study intends to evaluate Dexmedetomidine, a highly selective - 2 receptor agonist, that is currently applied safely and efficiently in intraoperative cardiac surgery. It has analgesic, sedative, anxiolytic …

pain relieving
dexmedetomidine
cardiopulmonary bypass
sedative
acute pain
  • 0 views
  • 28 Oct, 2021
  • 2 locations
Effect of Dobutamine on Hepatic Blood Flow During Goal-directed Hemodynamic Therapy

Maintaining adequate perfusion pressure and oxygen supply is essential for organ survival. Splanchnic hypoperfusion during the perioperative period in abdominal surgery may result in mucosal ischemia with increased permeability of the gut barrier. Additionally, the liver is also sensitive for hypoxemia and hypoperfusion, especially during liver surgery. Anesthetics (such as …

  • 3 views
  • 18 Jul, 2021
  • 1 location