Found 164 clinical trials
The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias
drug called venetoclax. The purpose of this study is to see whether the study drug and venetoclax can work together to slow down the growth of cells that cause acute myeloid leukemia (AML).
- 4 views
- 23 Jul, 2021
- 3 locations
Venetoclax Lenalidomide and Rituximab in Patients With Relapsed/Refractory Mantle Cell Lymphoma
Phase I/II trial, with the aim of evaluating the efficacy of venetoclax to the backbone of rituximab-lenalidomide in patients with relapsed/refractory MCL.
- 3 views
- 26 Jan, 2021
- 22 locations
ObinutuzuMab AtezOlizumab and VenetocLax in RichTer transfOrmation
This study is a multicenter, open-label, uncontrolled, phase II trial aimed to establish the safety and tolerability of venetoclax, atezolizumab and obinutuzumab combination in Richter
- 0 views
- 27 Sep, 2021
- 20 locations
Study of Venetoclax a BCL2 Antagonist for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
This research study is studying a drug as a possible treatment for BPDCN. The intervention involved in this study is: Venetoclax
- 40 views
- 16 May, 2021
- 1 location
Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)
This is an open-label Phase I dose-escalation study of oral venetoclax in combination with increasing cytarabine doses plus mitoxantrone to define the safety profile and MTD of cytarabine in
- 0 views
- 15 Sep, 2021
- 2 locations
Venetoclax SL-401 and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm
This phase II trial studies how well venetoclax, SL-401, and chemotherapy works in treating patients with blastic plasmacytoid dendritic cell neoplasm. Venetoclax may stop the growth of tumor
- 0 views
- 30 Jan, 2021
Palbociclib Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer
This study is investigating the combination of palbociclib, letrozole and venetoclax in ER and BCL-2 positive locally advanced or metastatic breast cancer. It is hypothesised that
- 45 views
- 24 Jan, 2021
- 3 locations
Pegcrisantaspase in Combination With Venetoclax for Treatment of Relapsed or Refractory Acute Myeloid Leukemia (R/R AML)
Evaluate the safety and tolerability of pegcrisantaspase in combination with venetoclax (Ven-PegC) and estimate the maximum tolerated doses and/or biologically active doses of Ven-PegC in
- 0 views
- 21 May, 2021
- 1 location
Study of Magrolimab Combinations in Participants With Myeloid Malignancies
therapies of venetoclax (Ven) and azacitidine (Aza) (Cohort 1), mitoxantrone, etoposide, and cytarabine (MEC) (Cohort 2) and CC-486 (Cohort 3) respectively in participants with acute myeloid leukemia (AML
- 0 views
- 01 Sep, 2021
- 2 locations
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
The aim of this study is to compare the efficacy of continuous ibrutinib monotherapy with fixed-duration venetoclax plus obinutuzumab and fixed-duration ibrutinib plus venetoclax by measuring
- 1 views
- 30 Mar, 2021
- 1 location