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Found 187 clinical trials
Featured trial
The Axcelsius Study: A Study of ONO-7475 in Patients with Acute Leukemias

drug called venetoclax. The purpose of this study is to see whether the study drug and venetoclax can work together to slow down the growth of cells that cause acute myeloid leukemia (AML).

blast cells
myeloid leukemia
induction chemotherapy
cancer
refractory acute myeloid leukemia (aml)
  • 21 views
  • 11 Jan, 2022
  • 4 locations
  • 6 views
  • 28 Jul, 2022
  • 20 locations
ObinutuzuMab AtezOlizumab and VenetocLax in RichTer transfOrmation (MOLTO)

This study is a multicenter, open-label, uncontrolled, phase II trial aimed to establish the safety and tolerability of venetoclax, atezolizumab and obinutuzumab combination in Richter

  • 0 views
  • 21 Feb, 2022
  • 16 locations
CC-486 and Venetoclax for Acute Myeloid Leukemia

This is an open label, dose escalation Phase I single institution pilot study for relapsed and refractory AML patients using CC-486 (oral azacitidine) with venetoclax. At the completion of dose

  • 0 views
  • 20 Apr, 2022
  • 2 locations
Venetoclax Based Regimen for R/R T-ALL

This study is to investigate the therapeutic efficacy and side effect of venetoclax based regimen for relapsed or refractroy T cell acute lymphoblastic leukemia.

  • 0 views
  • 15 Dec, 2021
  • 1 location
Palbociclib Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer

This study is investigating the combination of palbociclib, letrozole and venetoclax in ER and BCL-2 positive locally advanced or metastatic breast cancer. It is hypothesised that

neutrophil count
gilbert's syndrome
carcinoma
local therapy
metastasis
  • 45 views
  • 24 Jan, 2021
  • 3 locations
Rituximab + High-Dose Methylprednisolone Debulking Prior to Venetoclax for CLL & SLL Patients

prior to starting venetoclax, and therefore make it safer to take venetoclax. Patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) will be treated

  • 0 views
  • 14 Apr, 2022
  • 1 location
Venetoclax SL-401 and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

This phase II trial studies how well venetoclax, SL-401, and chemotherapy works in treating patients with blastic plasmacytoid dendritic cell neoplasm. Venetoclax may stop the growth of tumor

  • 0 views
  • 09 Dec, 2021
  • 1 location
Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)

This is an open-label Phase I dose-escalation study of oral venetoclax in combination with increasing cytarabine doses plus mitoxantrone to define the safety profile and MTD of cytarabine in

induction chemotherapy
refractory acute myeloid leukemia (aml)
cytarabine
mitoxantrone
cell transplantation
  • 8 views
  • 15 Sep, 2021
  • 4 locations
Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia (VEN-OM)

participants with relapsed/refractory hematologic malignancies including those failing treatment with venetoclax-containing regimens. Treatment plan will consist of an induction phase, followed by a

  • 0 views
  • 25 May, 2022
  • 1 location