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Found 133 clinical trials
A Reinforcement Intervention for Increasing HIV Testing Among At-Risk Women

risk factors are present, including other sexually transmitted infections, intimate partner violence, substance use disorders, and homelessness or housing insecurity. Knowledge of one's HIV serostatus

venereal disease
hiv test
HIV Vaccine
AIDS
AIDS prevention
  • 14 views
  • 11 Jul, 2022
  • 1 location
Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV (EVA)

The study team's prior research has shown that dysfunction of a specific nerve, called the vagus nerve, is associated with small intestinal bacterial overgrowth (SIBO), and that SIBO is associated with signs of inflammation in the blood of people living with HIV (PLWH). This research will explore pathways linking vagal …

diabetes
hiv-1 infection
Accepts healthy volunteers
opioid
HIV Vaccine
  • 38 views
  • 01 May, 2022
  • 1 location
Pre-exposure Prophylaxis (PrEP) at Home (PrEP@Home)

This study is a randomized clinical trial of PrEP@Home, a home care system for Human Immunodeficiency Virus (HIV) Pre-Exposure Prophylaxis (PrEP). Individuals entering into PrEP care at an initial in-person study visit will be randomized to the PrEP@Home system for home-based PrEP care follow-up visits or to the control standard …

immunodeficiency
AIDS prevention
pre-exposure prophylaxis (prep)
Accepts healthy volunteers
HIV Infection
  • 31 views
  • 04 Oct, 2022
  • 4 locations
Clinical Trial to Evaluate the Efficacy and Safety of a 4-channel Swallowing Function Electrical Stimulation Device Compared to a 2-channel Swallowing Function Electrical Stimulation Device for the Rehabilitation Mechanism

This study is a pilot study to prepare clinical trials to evaluate the safety and effectiveness of 4-channel electric stimulation therapy devices as a newly developed function for the treatment of dysphagia disorders. The purpose of this study is to investigate the difference in effect by the electric stimulation method …

Accepts healthy volunteers
  • 0 views
  • 15 Oct, 2022
  • 1 location
Sexual Confidence: CBT for Social Anxiety Disorder With HIV Risk Reduction Counselling for HIV-negative gbMSM (SC-RCT)

Given the continued high human immunodeficiency virus (HIV) prevalence rates among gay, bisexual, and other men who have sex with men (MSM) in North American cities, there is a critical need for HIV prevention interventions for MSM in Canada. Social anxiety, or anxiety about being evaluated in interpersonal and performance …

immunodeficiency
pre-exposure prophylaxis (prep)
Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
A Multicomponent Intervention to Increase HIV Risk Perceptions and PrEP Initiation Among Black Men Who Have Sex With Men

Tragically, HIV infections among Black sexual minority men (BSMM) in the U.S. persist. Despite the availability of pre-exposure prophylaxis (PrEP) for HIV prevention, effective uptake among BSMM remains low. It is imperative to support PrEP initiation among this group. The proposed multi-component interventional study is designed to increase HIV risk …

Accepts healthy volunteers
  • 0 views
  • 16 Oct, 2022
  • 1 location
Pharmacy-based Pre-exposure Prophylaxis

The proposed research will develop a culturally appropriate pharmacy PrEP delivery model for black men who have sex with men (BMSM) who live in high poverty, racial minority neighborhoods. Increasing access to PrEP through pharmacies has the potential to increase PrEP uptake among BMSM thereby reducing HIV incidence and racial …

hiv test
pre-exposure prophylaxis (prep)
gonorrhea
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 1 Cellular Immunotherapy Study of Intraventricularly Administered Autologous HER2-Targeted Chimeric Antigen Receptor (HER2-CAR) T Cells in Patients With Brain and/or Leptomeningeal Metastases From HER2 Positive Cancers

This phase I trial studies the side effects and best dose of HER2-CAR T cells in treating patients with cancer that has spread to the brain or leptomeninges and has come back (recurrent). HER2-CAR T cells delivered into the ventricles of the brain may recognize and kill tumor cells.

dexamethasone
neuropathy
mammogram
tumor cells
neutrophil count
  • 48 views
  • 18 Oct, 2022
  • 1 location
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment Acute Respiratory Distress Syndrome

This is a phase I trial followed by a phase II randomized trial. The purpose of phase I study is the feasibility of treating patients with acute respiratory distress syndrome (ARDS) related to COVID-19 infection (COVID-19) with cord blood-derived mesenchymal stem cells (MSC). The purpose of the phase II trial …

cancer
experimental drug
  • 7 views
  • 23 Oct, 2022
  • 1 location
Daratumumab for First Line Treatment of Transplant-ineligible Myeloma Patients Followed by Daratumumab Re-treatment at First Relapse (GMMG-DADA)

Daratumumab for first line treatment of transplant-ineligible myeloma patients followed by daratumumab re-treatment at first relapse (GMMG-DADA)

lenalidomide
dexamethasone
bortezomib
  • 0 views
  • 23 Apr, 2022
  • 1 location