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Found 275 clinical trials
Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

In this study, we aim to evaluate the efficacy and safety of an individualized dosing schedule comprising Aflibercept and RF-PDT in patients with polypoidal choroidal vasculopathy (PCV). The objective is to compare the visual improvement from baseline to month 12, in eyes with PCV treated with Aflibercept monotherapy versus combination …

  • 0 views
  • 10 Jun, 2021
  • 3 locations
Sequences Of REGorafenib And Trifluridine/Tipiracil in Patients With Metastatic Colorectal Cancer

A randomized, phase II study comparing the sequences of regorafenib and trifluridine/tipiracil, after failure of standard therapies in patients with metastatic colorectal cancer

heparin
metastasis
tipiracil
platelet count
vascular endothelial growth factor
  • 0 views
  • 25 May, 2021
  • 21 locations
Extension Study of MYL-1701P-3001 for Safety and Efficacy

This Study (AFIL-IJZ-3002) is designed to evaluate the safety, efficacy and immunogenicity of MYL-1701P among a group of participants successfully completing MYL-1701P-3001 study.

  • 0 views
  • 27 May, 2021
  • 13 locations
Intravitreal Bevacizumab Combined With PDT Versus Bevacizumab to Treat Exudative AMD

The purpose of this study is to determine the association of bevacizumab and PDT is safety and effective in the treatment of exudative AMD

bevacizumab
corrected visual acuity
neovascularization
  • 10 views
  • 07 Nov, 2020
  • 1 location
Intravitreal Bevacizumab Vs Photocoagulation for Proliferative Diabetic Retinopathy

The purpose of the study is to evaluate the safety and efficacy of 2.5 mg of intravitreal bevacizumab in one eye, versus panretinal photocoagulation in the contralateral eye, for the treatment of patients with untreated symmetric proliferative diabetic retinopathy.

bevacizumab
photocoagulation
diabetic retinopathy
retinopathy
proliferative diabetic retinopathy
  • 18 views
  • 07 Nov, 2020
  • 1 location
Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma

The purpose of this study is to evaluate the efficacy and safety of avastin combined with gemcitabine, oxaliplatin, pegaspargase and dexamethasone(Avastin+ GemAOD) as first-line treatment in patients with untreated natural killer(NK)/T cell lymphoma

  • 9 views
  • 07 Nov, 2020
  • 1 location
Doxycycline for Hereditary Hemorrhagic Telangiectasia

This study will investigate the effectiveness of oral doxycycline for the treatment of recurrent nasal hemorrhage in Hereditary Hemorrhagic Telangiectasia (HHT) subjects. The primary outcome for the trials will be the reduction of epistaxis severity (minutes of bleeding per week). The biological outcomes of interest are the regression of vascular …

  • 2 views
  • 25 Jan, 2021
  • 1 location
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Non-Small Cell Lung Cancer

The purpose of this study is to evaluate the safety and time to progression of HLA-A*0201 restricted epitope peptides URLC10, VEGFR1 and VEGFR2 emulsified with Montanide ISA 51.

VEGFR2
platelet count
  • 32 views
  • 07 Nov, 2020
  • 1 location
Treatment of Erectile Dysfunction in Hypogonadal Men With Testosterone Undecanoate

The main objective of this study is to evaluate the response of erectile dysfunction in hypogonadotrophic males with Testosterone undecanoate i.m. as per IIEF and the question of the GAQ (Global Evaluation Questionnaire) after 42 weeks of treatment. Secondary Study Objectives - To monitor adverse events and changes in hemoglobin …

testosterone
hypogonadism
  • 209 views
  • 07 Nov, 2020
  • 2 locations
The IPLA-OVCA Trial Intra-Peritoneal Local Anaesthetics in Ovarian Cancer

Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour. Radical resection of all tumour visible by the naked eye followed by adjuvant chemotherapy is associated with best chance of prolonged survival. …

metastasis
cancer of the ovary
surgery for ovarian cancer
cytoreductive surgery
ovarian cancer stage
  • 0 views
  • 30 Jan, 2021
  • 1 location