Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 254 clinical trials
featured
A Phase 2a, Double-blind, Randomized, Placebo-controlled, Proof of Concept Study of Vascular Endothelial Growth Factor (VEGF)-B Blockade with the Monoclonal Antibody CSL346 in Subjects with Diabetic Kidney Disease.

We are currently recruiting participants for a clinical research study to evaluate the efficacy of an investigational medication in adults with Diabetic Kidney Disease.

diabetic complication
diabetes
diabetic chronic kidney disease
diabetic complications
kidney function tests
  • 12 views
  • 14 Jan, 2021
  • 1 location
featured
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

of agents such as VEGF, mTOR inhibitors and immunotherapy (high-dose (HD) IL-2 or immune-checkpoint inhibitors). Long-term survival can be achieved with high-doses IL-2 or immune-checkpoint inhibitors

renal cell cancer
clear cell carcinoma
metastatic cancer
primary cancer
clear cell renal cell carcinoma
  • 144 views
  • 22 Dec, 2020
  • 1 location
Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

-cell component, who progressed after prior Checkpoint Inhibitors (CPI) therapy with ipilimumab and nivolumab in combination or CPI combined with Vascular Endothelial Growth Factor (VEGF)-targeted

  • 2 views
  • 05 Dec, 2020
  • 67 locations
Correlation of VEGF-A and Fluid Balance in Septic Shock

VEGF is a key molecule in the control of vascular permeability via interactions with the VEGF-receptor on the endothelial cell. Several authors reported plasma VEGF levels are elevated in sepsis

antibiotic therapy
vasoconstrictor
antibiotics
sepsis
  • 0 views
  • 04 Nov, 2020
  • 1 location
Angiogenic Factor Expression During Fractionated Irradiation

The main question of this study is if and when VEGF (vascular endothelial growth factor) expression in the tumor is upregulated during chemoradiation and if bevacizumab inhibits subsequent

  • 0 views
  • 23 Jan, 2021
  • 3 locations
The Study of Drug 601 in Patients With Wet Age-related Macular Degeneration (wAMD)

Multicenter study to evaluate the safety and tolerability in patients with wet Age-related macular degeneration (wAMD) treated with intravitreal recombinant humanized anti-VEGF monoclonal

  • 0 views
  • 25 Jan, 2021
Intravitreal Conbercept Injection in Patients With Myopic Choroidal Neovascularization

-vascular endothelial growth factor (VEGF) drugs would significantly suppress the activity of the CNV and finally improve the visual acuity. However, more than half of the patients would need one or more

  • 0 views
  • 23 Jan, 2021
  • 1 location
Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome

blindness by suppressing the neovascular phase of ROP the visual outcomes after treatment are often poor. Vascular endothelial growth factor(VEGF) has an important role in the pathogenesis of ROP

antiangiogenic therapy
vegf
bevacizumab
blindness
vascular endothelial growth factor
  • 4 views
  • 07 Nov, 2020
  • 1 location
Impact of Endostar Combined With Chemotherapy on the Angiogenesis of Advanced Non-small Cell Lung Cancer (NSCLC)

combined with docetaxel and cisplatin) and group two (docetaxel and cisplatin). - The serum concentrations of Endostatin,VEGF and bFGF are determined. - Blood circulating endothelial

stage iv non-small cell lung cancer
docetaxel
neutrophil count
tumor angiogenesis
lung cancer
  • 11 views
  • 07 Nov, 2020
  • 1 location
Eylea and Lucentis for Macular Edema in Branch Retinal Vein Occlusion

Comparing time to recurrence of macular edema after an initial loading dose of at least three monthly anti VEGF injections (aflibercept or ranibizumab) for macular edema in BRVO.

  • 0 views
  • 13 Dec, 2020
  • 1 location