Found 34 clinical trials
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
A Phase 4 Open-Label Study to Evaluate Vedolizumab IV Dose Optimization on Treatment Outcomes In Nonresponders With Moderately to Severely Active Ulcerative Colitis (ENTERPRET)
A Phase 4 Open-Label Study to Evaluate Vedolizumab IV Dose Optimization on Treatment Outcomes In Nonresponders With Moderately to Severely Active Ulcerative Colitis (ENTERPRET)
- 82 views
- 08 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
A Phase 3 Clinical Trial for Patients with Moderately to Severely Active Ulcerative Colitis
A Phase 3 Clinical Trial for Patients with Moderately to Severely Active Ulcerative Colitis
- 170 views
- 08 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
A Phase 3 Clinical Trial for Patients with Moderately to Severely Active Crohn's Disease.
A Phase 3 Clinical Trial for Patients with Moderately to Severely Active Crohn's Disease.
- 274 views
- 08 Nov, 2020
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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Currently Recruiting
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
Phase III, Double Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Etrolizumab During Induction and Maintenance in Patients With Moderate to Severe Active Ulcerative Colitis Who Are Refractory to or Intolerant of TNF Inhibitors
- 182 views
- 23 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Vedolizumab in the Prophylaxis of Intestinal Acute Graft Versus Host Disease (aGVHD) in Participants Undergoing Allogeneic Hematopoietic Stem Cell (Allo-HSCT) Transplantation
The purpose of this study is to evaluate the efficacy of vedolizumab when added to background aGvHD prophylaxis regimen compared to placebo and background aGvHD prophylaxis regimen on intestinal
- 42 views
- 28 Oct, 2020
- 113 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Defining Predictors of RT Response to Vedolizumab in IBD
The overall goal of the study is to develop data that can convincingly guide clinicians on the use and efficacy of vedolizumab in patients with small bowel CD. There is an unmet need to identify
- 12 views
- 24 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis
The purpose of this study is to assess the effect of vedolizumab intravenous IV as induction and maintenance treatment in Chinese participants with moderately to severely active ulcerative
- 8 views
- 01 Nov, 2020
- 20 locations
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Multi-country trial
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Unknown Phase
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Gastroenterology
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Currently Recruiting
Predicting Response to Vedolizumab in Pediatric Inflammatory Bowel Diseases
Vedolizumab (VDZ) is a humanized immunoglobulin G1 monoclonal antibody acting against 47 integrin which modulates lymphocyte trafficking in the gut. Results from the adult GEMINI-1 and
- 129 views
- 22 Jan, 2021
- 13 locations
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Dose-Ranging Phase 2b Study of ABX464 in Moderate to Severe Ulcerative Colitis
Phase IIb study to evaluate the efficacy and the safety of 3 dose-levels of ABX464, administered daily in patients with moderate to severe Ulcerative Colitis.
- 132 views
- 24 Jan, 2021
- 163 locations
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Unknown Phase
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Infections and Infectious Diseases
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Currently Recruiting
Fecal Microbial Transplantation and Vedolizumab Treatment of Crohn's Disease
The investigators postulate that by determining a patient's baseline microbiome and manipulating it through fecal microbial transplantation (FMT) may improve response rates to vedolizumab in
- 10 views
- 24 Jan, 2021
- 2 locations