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Found 83 clinical trials
Simple Observational Critical Care Studies (SOCCS)

Each year approximately 3000 patients are admitted to the intensive care unit (ICU) in the University Medical Center Groningen (UMCG). In-hospital mortality of patients with emergency admission approaches 25%. Predicting outcome in the first hours after ICU admission, however, remains a challenge. An vast amount of scoring systems has been …

critical illness
organ failure
acute renal failure
  • 04 Mar, 2022
  • 1 location
NT-proBNP and Troponin I in Dengue Children

, respiratory support, using inotrope and vasopressor using.

  • 18 Apr, 2021
  • 1 location
ST Elevation Myocardial Infarction Hemodynamic OutComes: Role of Non-Invasive Cardiac System (SHOCk-NICaS) Study

of 1.8L/min/m2 or 2.2L/min/m2 with the use of vasopressor and/or inotropes, and compare it with the incidence of CS based upon lactate level 2mmol/L, and systolic blood pressure <90mmHg; b

  • 25 Jan, 2021
  • 1 location
Sepsis in the ICU-II

from previous cardiovascular disease, vasopressor and inotropic drugs and mechanical ventilation. Another poorly investigated area is right ventricular dysfunction. Cor pulmonale occurs in up to 25% of

systolic dysfunction
septic shock
  • 31 Oct, 2021
  • 1 location
Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

This study aims to find out whether the use of angiotensin II, which is a drug to raise blood pressure has been approved by European Medical Agency in August 2019, as an add-on medication to increase blood pressure in patients with COVID-19, acute severe lung injury, inflammation and severe shock, …

respiratory distress
lung injury
  • 15 Aug, 2021
  • 1 location
Effect of Norepinephrine Administration on Ventricular Systolic Function in Septic Shock

This observational, pharmacological, prospective study aims to assess the improvement of ventricular systolic function mediated by norepinephrine (NE) administration in preload non-responders septic shock patients. Left ventricular outflow tract velocity time integral (LVOT-VTI) is an echocardiographic index of ventricular systolic function and it will be measured at different NE dosages.

  • 10 May, 2022
  • 1 location
Endothelial Function Inflammation and Organ Dysfunction in COVID-19

COVID-19 is a rapidly evolving pandemic with approximately 5% of all patients which require intensive care unit admission. In critically ill patients infected with COVID-19, approximately 15% had severe shock requiring medications to increase blood pressure. It appears that blood vessel tone is altered and microcirculation is not well regulated …

  • 16 Aug, 2021
  • 1 location
Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension

In critically ill patients with liver disease like cirrhosis or ACLF, fluid therapy needs to be instituted after identification of patients who will be fluid responsive and initiate appropriate inotropes early to prevent the mortality associated with fluid overload. The parameters and methodology used for assessing fluid responsiveness have been …

systolic blood pressure
liver disease
  • 06 Jun, 2022
  • 2 locations
Dynamic Estimation of Cardiac Output in the Operating Room

During major surgery, it is recommended to monitor invasive arterial blood pressure and cardiac output (CO) during hemodynamic interventions (fluid challenge or vasopressors). Esophageal Doppler is currently considered as the reference method for monitoring cardiac output in the operating room. The PRAM method (pressure recording analytical method) with the MostCareUp …

  • 24 Oct, 2021
  • 1 location
Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy (TECHNO-HDF)

This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absolute blood volume (ABV), and 3) change in carotid Doppler at the start of IKRT to predict IDHE in acutely ill hospitalized patients. …

  • 27 Apr, 2022
  • 1 location