Found 123 clinical trials
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine
Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine
- 346 views
- 25 Mar, 2021
- 1 location
Efficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab. (MANDARA)
This is a randomized, double blind, active-controlled, parallel group, multicenter 52-week Phase 3 study to compare the efficacy and safety of benralizumab 30 mg versus mepolizumab 300 mg administered by subcutaneous (SC) injection in patients with relapsing or refractory EGPA on corticosteroid therapy with or without stable immunosuppressive therapy. All …
- 65 views
- 06 May, 2022
- 70 locations
COVID-19 VACCINE SAFETY AND EFFECTIVENESS
A longitudinal open-label study will include health professionals and patients with immune-mediated inflammatory diseases (IMID) who will receive the ChAdOx1 nCoV-19 vaccine (AZD1222), in a standard 3-dose schedule with an interval of 12 weeks (first-second dose) and 24 weeks (second-thrid dose), in the vaccination campaign against SARS-CoV-2 to assess the …
- 0 views
- 02 Dec, 2021
- 1 location
Efficacy of Colchicine to Prevent Skin Relapses in Adult's IgA Vasculitis
Immunoglobulin A vasculitis (IgA-V), formerly called Henoch-Schnlein purpura, is an immune vasculitis. Relapses are frequent (30%) and most of the time cutaneous (90%). Cutaneous involvement in
- 0 views
- 10 Oct, 2021
- 1 location
Evaluation of Glucocorticoids Plus Rituximab Compared to Glucocorticoids Plus Placebo for the Treatment of Patients With Newly-Diagnosed or Relapsing IgA Vasculitis (RIGA)
Systemic vasculitis are inflammatory diseases of the blood vessels, responsible for systemic manifestations. Among the systemic vasculitis affecting small blood vessels, IgA vasculitis (IgAV) is
- 0 views
- 29 Apr, 2022
- 1 location
Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic Antibodies (ANCA)-Associated Vasculitis. (MAINEPSAN)
vasculitis patients with relapses. Nevertheless, it was an indirect estimation of treatment effect because of the absence of dedicated randomized trial. This meta-analysis concluded that combined longer
- 0 views
- 15 Feb, 2022
- 20 locations
Methylprednisolone Pulse Therapy for Coronary Artery Dilatation or Aneurysm Formation in Kawasaki Disease
investigate the role for vasculitis of KD or regression of dilatation.
- 33 views
- 25 Jan, 2021
- 1 location
Study of T Lymphocytes in Patients With Horton Disease (GAMAIT)
Giant-cell arteritis (GCA) is the most frequent vasculitis after 50 years. Corticosteroid therapy is the reference treatment for GCA. This treatment is highly effective but must be maintained
- 1 views
- 04 Mar, 2022
- 1 location
Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura
IgA vasculitis is relatively common in children,especially in Asian countries. Abdominal manifestation could be severe, including bleeding, pancreatitis,appendicitis and intestinal
- 0 views
- 23 Mar, 2022
- 1 location
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis (ULTRA)
Giant cell arteritis (GCA) is the most common form of vasculitis after age 50. It is a vasculitis affecting the large vessels, in particular the aorta and its collateral vessels, especially
- 0 views
- 26 Apr, 2022
- 1 location