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Found 189 clinical trials
Intravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment Repair

growth factor (PDGF) by vascular endothelial growth factor (VEGF) potentiates a pathologic, sustained activation of PDGF receptors that is critical to the progression of experimental PVR. VEGF blockade

  • 0 views
  • 26 Jan, 2021
  • 1 location
Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features.

endothelial growth factor-A (VEGFA), vascular endothelial growth factor-R2 (VEGFR2), stromal cell-derived factor 1 (SDF1) and chemokine receptor-4 (CXCR4) will be analyzed by enzyme-linked immunosorbent assay

vascular endothelial growth factor
primary brain tumors
MRI
glioblastoma multiforme
growth factor
  • 1 views
  • 22 Jan, 2021
  • 2 locations
MMP-9 Inhibition for Recalcitrant Wet AMD

Wet (or neovascular) form of age-related macular degeneration (wAMD) is the most common cause of blindness in the Western world. Currently, anti-vascular endothelial growth factor (VEGF

  • 0 views
  • 19 Feb, 2021
  • 1 location
Sorafenib With Capecitabine and Oxaliplatin for Advanced or Metastatic Hepatocellular Carcinoma

vascular endothelial growth factor (VEGF) are both overexpressed in HCC and thought to contribute to tumor development. Oxaliplatin in combination with other chemotherapies or biologic agents

  • 1 views
  • 07 Nov, 2020
  • 1 location
The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns

macrophage infiltration, burns depth assessment and vascular endothelial growth factor (VEGF) and inducible nitric oxide synthase (iNOS) . - Study the effects of HBOT on bacteriology of

  • 10 views
  • 07 Nov, 2020
  • 1 location
SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes

these SMOKIs (small molecule oral kinase inhibitors) block vascular endothelial growth factor and platelet derived growth factors receptors (VEGFRs and PDGFRs), speaking to a common mechanism of action

small molecule
measurable disease
ewing's sarcoma
pazopanib
x-rays
  • 150 views
  • 27 Jan, 2021
  • 16 locations
Combination Neoadjuvant Chemotherapy With or Without Apatinib for HER2 Negative Breast Cancer

-negative breast cancer patients. Apatinib is a highly potent human vascular endothelial growth factor receptor 2 (VEGFR2) tyrosine kinase inhibitor that has been independently developed in China, and it

erbb2
growth factor
paclitaxel
HER2
breast adenocarcinoma
  • 6 views
  • 23 Jan, 2021
  • 1 location
Testing the Combination of Cabozantinib Nivolumab and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer

worsened after treatment with a drug targeting the vascular endothelial growth factor receptor (VEGFR), a protein needed to form blood vessels. Cabozantinib may stop the growth of tumor cells by blocking

calcium
follicle stimulating hormone
measurable disease
pazopanib
prothrombin
  • 4 views
  • 28 Jan, 2021
  • 7 locations
Mesenchymal Stem Cell-derived Pleiotropic Factor in the Treatment of Donor Sites

mainly through paracrine. Many biological effectors, including IGF-1, vascular endothelial growth factor (VEGF), TGF-1, and hepatocyte growth factor (HGF), have been found and reported in various MSC

  • 0 views
  • 24 Jan, 2021
  • 1 location
Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Residual Burn Wound

) boost tissue repair through paracrine. Many biological effectors, including IGF-1, vascular endothelial growth factor (VEGF), TGF-1 have been found in MSC conditioned media (MSC-CM), and play a role in

  • 0 views
  • 24 Jan, 2021
  • 1 location