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Found 188 clinical trials
The IPLA-OVCA Trial Intra-Peritoneal Local Anaesthetics in Ovarian Cancer

Surgery and chemotherapy combined constitute first line treatment in women with advanced ovarian cancer. The aim of surgery apart from staging is cytoreduction, i.e. surgical resection of tumour. Radical resection of all tumour visible by the naked eye followed by adjuvant chemotherapy is associated with best chance of prolonged survival. …

cytoreductive surgery
fallopian tube
surgery for ovarian cancer
ovarian cancer stage
  • 30 Jan, 2021
  • 1 location
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial)

Greater Trochanteric Pain Syndrome (GTPS), also known as Trochanteric Bursitis, is a painful condition predominantly affecting middle aged women. It is characterised by pain in the lateral hip exacerbated by movement and lying on the affected side. GTPS encompasses different conditions including gluteus medius/minimus tendinopathy and bursal inflammation. The treatment …

  • 23 Jan, 2021
  • 1 location
Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease

This phase 2a, double-blind, randomized, placebo-controlled study will assess the efficacy, safety, tolerability, and pharmacokinetics (PK), of repeat doses of CSL346 in subjects with diabetic kidney disease (DKD) and albuminuria receiving standard of care treatment.

hemoglobin a1c
type 2 diabetes mellitus
vascular endothelial growth factor
  • 31 Jan, 2021
  • 42 locations
Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)

received anti-VEGF (vascular endothelial growth factor) treatment. Patients who consent will undergo screening assessments to evaluate their eligibility based on the inclusion and exclusion criteria.

diabetic retinopathy
retinal pigment
corrected visual acuity
  • 03 Mar, 2021
  • 123 locations
A Study to Comparing SCD411 and Eylea in Subjects With Wet Age-related Macular Degeneration (AMD)

damages and scars the macula, affecting vision. The current standard of care for patients with neovascular (exudative / wet) AMD is anti-vascular endothelial growth factor (anti-VEGF) therapy, which

  • 27 Jan, 2021
  • 76 locations
Cohort Study of the Clinical Course of Macular Diseases in Kagawa

Macular diseases often cases severe visual impairment. Recent clinical introduction of anti-vascular endothelial growth factor agents may change the clinical course of various macular diseases

  • 22 Jan, 2021
  • 1 location
Activity Study of Bevacizumab With Temozolomide Irinotecan for Neuroblastoma in Children

questions: does targeting blood vessel development using bevacizumab, (a monoclonal antibody against the Vascular Endothelial Growth Factor (VEGF)), add to the effect on a tumour when used

granulocyte colony stimulating factor
bone marrow disease
neutrophil count
  • 24 Jan, 2021
  • 10 locations
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix

The study will integrate the efficacy of combining the anti programmed death-ligand 1 (anti-PD-L1) agent atezolizumab with the current standard of care in Stage IVB , persistent or recurrent carcinoma of the cervix, namely cisplatin or carboplatin/paclitaxel/bevacizumab. It will be explored the combination of bevacizumab plus atezolizumab, with no patient …

  • 26 Jan, 2021
  • 90 locations
  • 26 Jan, 2021
  • 1 location
Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT

To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.

  • 24 Jan, 2021
  • 1 location