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Found 76 clinical trials
PICO Above Incisions After Vascular Surgery

incisions (INPWT) after vascular surgical procedures can reduce the risk for surgical site infections and other wound complications.

negative pressure wound therapy
wound infection
  • 2 views
  • 25 Jan, 2021
  • 2 locations
Effects of Ischemic Preconditioning After Aortic Clamping

Open surgery for aneurysmal aortic disease can lead to cardiac, renal, pulmonary or muscular complications, essentially due to the aortic clamping. Ischemic preconditioning can be useful in order to decrease these complications. The investigators would like to use an ischemic preconditioning protocol during open surgery of aortic aneurysm in order …

  • 0 views
  • 25 Jan, 2021
  • 4 locations
Australian and New Zealand Massive Transfusion Registry

Severe and un-stopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies. The investigators understanding of how to best treat people with serious bleeding is still incomplete, with many questions remaining. These include …

blood component
blood transfusion
  • 0 views
  • 25 Jan, 2021
  • 1 location
Measurement Of NT-proBNP to Predict Outcomes in Surgery

The team is investigating whether N-terminal pro B-type natriuretic peptide (NT-proBNP) and other cardiac markers are useful for predicting outcomes for patients undergoing vascular surgery. By measuring NT-proBNP before and after surgery, the investigators may be able to determine which patients are at risk of an adverse outcome, such as …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Evaluation of Effectiveness and Safety of Hybrid Coronary Revascularization

This study evaluated the effectiveness and safety of Hybrid Coronary Revascularization in real-world practice.

coronary revascularization
  • 0 views
  • 27 Jan, 2021
The TransCatheter Valve and Vessels Trial

The trial objective is to investigate whether Fractional Flow Reserve (FFR)-Guided Percutaneous Coronary Intervention (PCI) and TransCatheter Aortic Valve Implantation (TAVI) strategy for treatment of multivessel disease and aortic stenosis will be non-inferior to Coronary Artery By-pass Grafting (CABG) and Surgical Aortic Valve Replacement (SAVR) for a composite primary endpoint …

infarct
stroke
aortic valve replacement
transcatheter aortic valve implantation
stenosis
  • 52 views
  • 05 May, 2021
  • 26 locations
Optimal Strategy of Primary PCI for Left Main Coronary Artery Occlusion Induced AMI

This study will compare clinical outcomes of immediate stent implantation with deferred stent implantation(4-10days after primary angiography) for patients presented with acute myocardial infarction due to left main coronary artery occlusion.

infarct
aspiration
coronary artery occlusion
angiography
myocardial infarction
  • 0 views
  • 21 Jan, 2021
Adenosine Contrast CorrELations in Evaluating RevAscularizaTION

The purpose of this study is to compare FFR measurements done with adenosine to FFR measurements done with contrast, where the contrast is injected using the ACIST CVi automated contrast injector. The ACCELERATION study will support a safer approach to FFR for patients by potentially reducing toxic drug exposure (adenosine). …

adenosine
iopamidol
stenosis
  • 20 views
  • 09 Mar, 2021
  • 5 locations
Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention

During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI. However, a recent study has demonstrated the decrease in effectiveness of Ticagrelor when administered along with Fentanyl. Hence this study was designed to further assess the interaction between …

ticagrelor
  • 0 views
  • 11 Feb, 2021
  • 1 location
QFR-based Virtual PCI Versus Angio-guided PCI

A significant portion of patients continue to experience both adverse events and symptoms after angiographically successful PCI. Beyond different underlying mechanisms non-related to epicardial disease (vasospasm, microcirculatory dysfunction), several recent studies have shown that in at least 15-20% of PCIs, a prognostically meaningful ischemia, detected with different coronary physiology tools, …

  • 0 views
  • 08 May, 2021
  • 2 locations