Found 3568 clinical trials
Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)
The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein accumulation in older adults. Amyloid beta protein is high in the brain of older adults with Alzheimer's disease. Hypertension may increase brain amyloid …
- 114 views
- 07 Jul, 2022
- 1 location
Are you 65 or over with high cholesterol?
Are you 65 or over with high cholesterol?
- 198 views
- 08 Nov, 2020
- 1 location
Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank
Background: DNA tells the body how to grow and function. Williams-Beuren syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) are rare diseases caused by changes in a part of a person's DNA. Symptoms of both conditions include vascular problems including narrow blood vessels and supravalvular aortic stenosis (SVAS) or supravalvular pulmonary …
- 142 views
- 23 Nov, 2020
- 1 location
Men and Women ages 18 or older with High Blood Pressure and Diabetes Type 2 who DO NOT require the use of Insulin to control their Diabetes Levels
Men and Women ages 18 or older with High Blood Pressure and Diabetes Type 2 who DO NOT require the use of Insulin to control their Diabetes Levels
- 517 views
- 08 Nov, 2020
- 1 location
The Efficacy and Safety of Non-vItamiN K antaGonist oraL Anticoagulants for intermEdiate Stroke Risk in Patients With Atrial Fibrillation (SINGLE-AF)
-VASc score 1 for male, 2 for female). Major safety results include major bleeding and clinically relevant non-major bleeding. Major efficacy results include strokes, systemic
- 0 views
- 25 Jan, 2021
Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease
that established ASCVD patients (coronary artery disease, cerebrovascular disease, peripheral vascular disease) use high-dose statins to lower LDL cholesterol levels by at least 50%. However, in actual
- 0 views
- 12 Dec, 2021
- 2 locations
MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization (PARADIGM-EXT)
All-comer study of unselected patients suitable for carotid artery revascularization to evaluate the feasibility, efficacy and safety of first line endovascular revasculariztion using MicroNet covered stent (CGuard™) in the treatment of consecutive symptomatic and increased-stroke-risk asymptomatic carotid lesions that require revascularization by Neurovascular Team decision.
- 1 views
- 24 Apr, 2022
- 1 location
AnticoaguLation ONE Year After Ablation of Atrial Fibrillation in Patients With Atrial Fibrillation (ALONE AF Study)
There has no evidence for the anticoagulation in patients who had undergone catheter ablation of atrial fibrillation, and has maintained sinus rhythm for more than 1 year. However, anticoagulation can increase the risk of bleeding, the study evaluating the role of oral anticoagulation is needed in this patients. This study …
- 0 views
- 24 Jan, 2021
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
Individuals receiving dialysis are at risk of heart failure and heart related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis. Spironolactone is a pill used to prevent heart failure and related deaths in patients that do not require …
- 214 views
- 26 Jan, 2021
- 98 locations