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Found 71 clinical trials
The Effect of Intrawound Vancomycin Powder in Spine Surgery

concerns. Several methods for avoiding SSI, such as betadine irrigation, vacuum-assisted closure, and intra-wound vancomycin powder, have been used to reduce the rate of wound infection in spine surgery

  • 0 views
  • 16 May, 2022
  • 2 locations
Optimal Treatment for Recurrent Clostridium Difficile (OpTION)

The purpose of this study is to determine whether fidaxomicin and vancomycin followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment for the treatment of

  • 87 views
  • 24 Mar, 2022
  • 23 locations
Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty

This is a prospective, randomized, controlled, open label, parallel four-arm design, multi-center study to compare different intraoperative interventions in the prevention of acute PJI development.

joint reconstruction
avascular necrosis
  • 52 views
  • 13 Mar, 2022
  • 9 locations
Local Antibiotics for Breast Implants (BREAST-AB)

The BREAST-AB Trial is a multi-center, randomized, double blind, placebo-controlled trial investigating the efficacy of local application of gentamicin, vancomycin and cefazolin in decreasing

Accepts healthy volunteers
  • 179 views
  • 09 Jul, 2022
  • 3 locations
Study to Optimize the Use of New Antibiotics (NEW_SAFE)

carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa, carbapenem-resistant enterobacteria, vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus

ceftazidime-avibactam
isavuconazole
dalbavancin
antimicrobials
tedizolid
  • 3 views
  • 16 Feb, 2022
  • 13 locations
Carriage Clearance of Emerging Highly Resistant Bacteria in Chronic Dialysis Patients (DIACOBHR)

bacteremia in healthcare establishments in France at less than 1%, and that of Vancomycin Resistant Enterococcus (VRE) belonging to Enterococci Resistant to Glycopeptides (ERG) such as Enterococcus faecium

chronic renal failure
renal failure
strain
antibiotics
chronic dialysis
  • 0 views
  • 27 Apr, 2022
  • 5 locations
Infectious Diseases in Aged Population (AEQUI)

The increasing number of persons >65 years of age form a special population at risk for nosocomial and other health care-associated infections. The vulnerability of this age group is related to impaired host defenses such as diminished cell-mediated immunity. Lifestyle considerations, e.g., travel and living arrangements, and residence in nursing …

fever
blood culture
bacteremia
  • 0 views
  • 05 Jun, 2022
  • 16 locations
Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture (DAICY)

Rational for conducting the study: Periprosthetic joint infection (PJI) is the most feared complication following prosthetic replacement of the hip joint and is associated with increased mortality, morbidity and economic burden. The aim of the trial is to investigate whether the risk of periprosthetic joint infection after treatment with hemiarthroplasty …

  • 0 views
  • 27 May, 2022
  • 1 location
Precision Dosing of Vancomycin in Critically Ill Children (BENEFICIAL)

The overall objective of this project is to investigate the large-scale utility of MIPD of vancomycin at point-of-care in ICU children. This evaluation includes a comparison with the more

  • 0 views
  • 06 Jun, 2022
  • 6 locations
Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol

The objective of this study is to evaluate a novel vancomycin intraosseous administration protocol vs a standard IV vancomycin administration protocol for primary total hip arthroplasty patients

hip arthroplasty
total hip replacement
  • 3 views
  • 24 Feb, 2022
  • 1 location