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Found 71 clinical trials
Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

The objective is to examine the effect of Fecal Microbiota Transplantation (FMT) compared with vancomycin for cure of recurrent C. diff infection (CDI) in solid organ transplant (SOT) recipients

  • 23 Sep, 2022
  • 5 locations
Fecal Transplantation for Primary Clostridium Difficile Infection (COLONIZE)

the treatment of primary Clostridium difficile infection (CDI). The investigators hypothetsize that the instillation of feces from a healthy donor will be non-inferior to vancomycin in inducing a

stool test
fecal microbiota transplantation
antibiotic therapy
  • 10 May, 2022
  • 22 locations
An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection

urine and feces; To assess C. difficile using microbiological assessments; To assess the proportion of subjects colonized with vancomycin-resistant enterococci (VRE), extended

  • 20 Sep, 2022
  • 6 locations
Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery (PAPA)

INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction for all orthopaedic procedure with implantation of internal fixation device. With the increasing rate of identified P. acnes shoulder surgery infection despite the use of recommended skin preparation and preoperative prophylactic antibiotics, a question arises; Is Cefazolin …

  • 07 Jul, 2022
  • 1 location
Dropless Pars Plana Vitrectomy Study (DVS)

To demonstrate that intraoperative use of subtenon triamcinolone acetonide at the time of surgery without postoperative eye drops is non-inferior to the regimen of postoperative eye drops following primary pars plana vitrectomy for retinal detachment.

Accepts healthy volunteers
  • 12 Aug, 2022
  • 1 location
ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection

Segments 2A and 2B of this trial evaluate the safety, efficacy, pharmacokinetics, fecal concentrations, and fecal microbiome effects of ACX-362E [ibezapolstat] in patients with C. difficile infection (CDI).

stool test
  • 02 Jul, 2022
  • 15 locations
FMT in Initial CDI (FinCDI)

The study explores fecal microbiota transfer via retention enema after the first clostridioides difficile episode.

  • 11 Mar, 2022
  • 1 location
The Effect of Pretreatment for Propionibacterium Acnes on Surgical Site Burden in Shoulder Arthroplasty

Cutibacterium acnes - formally known as Propionibacter acnes (P. acnes) is the most common pathogen associated with prosthetic joint infection of the shoulder. Despite current skin preparation techniques, P. acnes is encountered at the skin surface and at the natural reservoir in the sebaceous glands during the surgical exposure; current …

  • 07 Jul, 2022
  • 2 locations
Infection Prevention After TKA With or Without Vancomycin (TKA_Vanco)

Prospective, Randomized, Double Blinded Trial Comparing Clinical, Radiological and Laboratory Outcomes in prevention of infection after Total Knee Arthroplasty With or Without Vancomycin.

Accepts healthy volunteers
  • 23 Jul, 2022
  • 1 location
Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty

The purpose of this study is to compare infection rates when patients, elected for primary or aseptic revision THA / TKA, have a single intravenous antibiotic dose versus one single intravenous antibiotic dose in combination with intra-articular antibiotics. This is a prospective, randomized clinical survey on selected outcome measurements on …

  • 21 Jul, 2021
  • 1 location