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Found 70 clinical trials
Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection (TAPER-V)

The first line therapy for an initial episode of CDI (Clostridium difficile infection) is 10-14 days of oral vancomycin which is now recommended over metronidazole in the 2018 guidelines from

  • 0 views
  • 21 Oct, 2022
  • 5 locations
Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial

  • 1 views
  • 04 Oct, 2022
  • 1 location
Screening to Prophylax Against Clostridium Difficile Infection - (StoP CDI)

The goal of this study is to evaluate whether using vancomycin orally can prevent CDI in patients who are colonized with C. diff who are admitted to the hospital and need antibiotics for another

ampicillin/sulbactam
clostridium difficile
antibiotic therapy
antibiotics
cephalosporin
  • 10 views
  • 10 Mar, 2022
  • 1 location
Vancomycin for Primary Sclerosing Cholangitis

To find out if vancomycin is a safe and effective therapy for primary sclerosing cholangitis. Funding Source - FDA OOPD

cholangiography
prednisone
bowel disease
ursodiol
steroid compound
  • 27 views
  • 07 Oct, 2022
  • 3 locations
Serum and Wound Vancomycin Levels Following Intrawound Administration in Primary Total Hip Arthroplasty

The purpose of this study is to determine the intra-articular and serum levels of vancomycin over the first 24 hours postoperatively after intra-articular administration of a standard dose of

  • 0 views
  • 18 Oct, 2022
  • 1 location
Oral Vancomycin vs Placebo in the Prevention of Recurrence of Clostridioides Difficile's Infection (PREVAN)

A phase III randomized clinical trial in proportion 2:1 in favor of oral vancomycin (experimental treatment), multicentric, national, double-blinded, controlled with placebo. The main objective

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Multicenter, Double-blinded, Randomized, Parallel Design, Phase IIa Clinical Trial to Evaluate the Efficacy, Safety and PK of LCB01-0371 With Vancomycin Versus Vancomycin Monotherapy in Patients With MRSA Bacteremia

The objectives of this study is to exploratory whether vancomycin + delpazolid is more effective to the standard of treatment (vancomycin)/ for hospitalised adults with MRSA bacteraemia.

  • 0 views
  • 11 Oct, 2022
  • 1 location
Topical Vancomycin Paste Over Sternal Edge: Safety and Effect of on Incidence of Sternal Wound Infection After Cardiac Surgery

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after

  • 0 views
  • 19 Oct, 2022
  • 1 location
A Phase 2, Randomized, Double-Blind, Comparator-Controlled, Multicenter Study to Evaluate the Safety and Efficacy of CRS3123 Compared With Oral Vancomycin in Adults With Clostridioides Difficile Infection

(bid) and vancomycin administered 125 mg PO 4 times daily (qid) in adults > or equal to 18 years of age with a primary episode or first recurrence of CDI. The study will investigate the plasma

  • 0 views
  • 15 Oct, 2022
  • 25 locations
Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

The objective is to examine the effect of Fecal Microbiota Transplantation (FMT) compared with vancomycin for cure of recurrent C. diff infection (CDI) in solid organ transplant (SOT) recipients

  • 3 views
  • 18 Oct, 2022
  • 5 locations