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Found 13 clinical trials
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An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis

An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis

  • 152 views
  • 08 Nov, 2020
  • 1 location
Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine

The objective of this study is to compare clinical efficacy and tolerability of valproic acid (VPA) therapy versus dihydroergotamine (DHE) as abortive therapy in pediatric migraine.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to determine whether Valproic acid, as a single agent is effective in the treatment of Chronic Lymphocytic Leukemia which has relapsed or is refractory to

nucleoside analog
lymphoid leukemia
cancer
platelet count
neutrophil count
  • 22 views
  • 07 Nov, 2020
  • 1 location
Avelumab With Valproic Acid in Virus-associated Cancer

to escape detection by a person's own immune system. One of the medications being studied in this clinical trial (Valproic acid) may be able to unmask a chronic viral infection from a person's own

carcinoma of cervix
anticoagulants
cancer
platelet count
measurable disease
  • 10 views
  • 22 Jan, 2021
  • 1 location
Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal Cancer

The primary aim of this study is to test whether the combination of valproic acid with bevacizumab and oxaliplatin/fluoropyrimidine regimens (mFOLFOX6/mOXXEL) can prolong progression free

  • 0 views
  • 24 Jan, 2021
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

This phase I trial studies the side effects and best dose of bevacizumab and temsirolimus alone or in combination with valproic acid or cetuximab in treating patients with a malignancy that has

type 2 neurofibromatosis
metastasis
absolute neutrophil count
neutrophil count
fasting
  • 60 views
  • 23 Jan, 2021
  • 1 location
International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)

neuroradiological survey. In addition to standard treatment (radiotherapy and temozolomide chemotherapy) the effect of valproic acid which is traditionally used for treatment of seizure

anaplastic astrocytoma
epilepsy
malignant glioma
astrocytoma
glioblastoma multiforme
  • 44 views
  • 30 Jan, 2021
  • 49 locations
Seizure Treatment in Glioma

patients. The overall aim of this randomized controlled trial is to directly compare the effectiveness of treatment with levetiracetam or valproic acid in glioma patients with a first seizure.

epilepsy
astrocytoma, anaplastic
anticonvulsants
astrocytoma
antiepileptic
  • 4 views
  • 27 Feb, 2021
  • 4 locations
Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics

This is an open-label, multi-center, phase I study designed to assess the maximum tolerated dose of ribociclib and belinostat in combination. The trial will open with a dose escalation followed by an expansion cohort at the identified dose. Dose escalation will be open to the enrollment of patients diagnosed with …

immunohistochemistry
breast cancer
metastasis
measurable disease
erbb2
  • 0 views
  • 26 Jan, 2021
  • 1 location
Study of Depakote for Behavioral and Psychological Symptoms in Dementia

This prospective, naturalistic, open label study will test the hypothesis that Depakote is correlated with a reduction in elevated Cohen-Mansfield Agitation Index (CMAI) verbal and physical agitation and aggression scales over a 6-week period among patients with elevated scores on those scales, and that these positive results can be achieved …

psychotropic drugs
dementia
psychological symptoms
mini-mental state examination
agitation
  • 23 views
  • 07 Nov, 2020
  • 1 location