Found 13 clinical trials
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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For all genders
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Currently Recruiting
An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis
An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis
- 152 views
- 08 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Valproic Acid and Dihydroergotamine as Abortive Therapy in Pediatric Migraine
The objective of this study is to compare clinical efficacy and tolerability of valproic acid (VPA) therapy versus dihydroergotamine (DHE) as abortive therapy in pediatric migraine.
- 0 views
- 24 Jan, 2021
- 1 location
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Hematology
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Currently Recruiting
Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)
The purpose of this study is to determine whether Valproic acid, as a single agent is effective in the treatment of Chronic Lymphocytic Leukemia which has relapsed or is refractory to
- 22 views
- 07 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Avelumab With Valproic Acid in Virus-associated Cancer
to escape detection by a person's own immune system. One of the medications being studied in this clinical trial (Valproic acid) may be able to unmask a chronic viral infection from a person's own
- 10 views
- 22 Jan, 2021
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Valproic Acid in Combination With Bevacizumab and Oxaliplatin/Fluoropyrimidine Regimens in Patients With Ras-mutated Metastatic Colorectal Cancer
The primary aim of this study is to test whether the combination of valproic acid with bevacizumab and oxaliplatin/fluoropyrimidine regimens (mFOLFOX6/mOXXEL) can prolong progression free
- 0 views
- 24 Jan, 2021
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Phase 1 trial
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For all genders
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Endocrinology
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Currently Recruiting
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
This phase I trial studies the side effects and best dose of bevacizumab and temsirolimus alone or in combination with valproic acid or cetuximab in treating patients with a malignancy that has
- 60 views
- 23 Jan, 2021
- 1 location
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Phase 3 trial
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Accepting pediatric ages
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)
neuroradiological survey. In addition to standard treatment (radiotherapy and temozolomide chemotherapy) the effect of valproic acid which is traditionally used for treatment of seizure
- 44 views
- 30 Jan, 2021
- 49 locations
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Phase 4 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Oncology
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Currently Recruiting
Seizure Treatment in Glioma
patients. The overall aim of this randomized controlled trial is to directly compare the effectiveness of treatment with levetiracetam or valproic acid in glioma patients with a first seizure.
- 4 views
- 27 Feb, 2021
- 4 locations
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Currently Recruiting
Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By Genomics
This is an open-label, multi-center, phase I study designed to assess the maximum tolerated dose of ribociclib and belinostat in combination. The trial will open with a dose escalation followed by an expansion cohort at the identified dose. Dose escalation will be open to the enrollment of patients diagnosed with …
- 0 views
- 26 Jan, 2021
- 1 location
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Phase 1 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Psychiatry/Psychology
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Currently Recruiting
Study of Depakote for Behavioral and Psychological Symptoms in Dementia
This prospective, naturalistic, open label study will test the hypothesis that Depakote is correlated with a reduction in elevated Cohen-Mansfield Agitation Index (CMAI) verbal and physical agitation and aggression scales over a 6-week period among patients with elevated scores on those scales, and that these positive results can be achieved …
- 23 views
- 07 Nov, 2020
- 1 location
- 1
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