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Found 27 clinical trials
Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma

This phase I trial studies the side effects and how well of pembrolizumab and a vaccine therapy (ATL-DC vaccine) work in treating patients with glioblastoma that has come back (recurrent) and

nitrosoureas
tumor cells
low grade glioma
metastatic disease
formalin-fixed paraffin-embedded
  • 9 views
  • 19 Apr, 2022
  • 1 location
HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

This randomized phase III trial studies how well human papillomavirus (HPV) vaccine therapy works in reducing high-grade cervical lesions in patients with human immunodeficiency virus (HIV) and

HIV Vaccine
hiv-1 rna measurement
antiretroviral therapy
antiretroviral
hiv test
  • 77 views
  • 23 Jul, 2022
  • 4 locations
Clinical Trial of Measles, Mumps and Rubella Combined Vaccine, Live

To evaluate the immunogenicity, lot-to-lot consistency and safety of three consecutive batches of Measles, Mumps and Rubella Combined Vaccine, Live.

measles
Accepts healthy volunteers
vaccination
rubella
  • 0 views
  • 12 Apr, 2022
  • 1 location
An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac)

An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac), Produced by FSBSI "Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products", on Volunteers at the Age of 18-60 Years

covid-19
Accepts healthy volunteers
vaccination
  • 0 views
  • 23 Jul, 2022
  • 9 locations
Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

The purpose of this research study is to determine if an investigational dendritic cell vaccine, called pp65 DC, is effective for the treatment of a specific type of brain tumor called glioblastoma (GBM) when given with stronger doses of routine chemotherapy.

sargramostim
brain tumor
MRI
dendritic cell vaccine
renal function
  • 498 views
  • 25 Mar, 2022
  • 2 locations
Neoantigen Vaccine Therapy Against H3.3-K27M Diffuse Intrinsic Pontine Glioma (ENACTING)

Diffuse intrinsic pontine gliomas (DIPGs), which diffusely occupy the pons of brainstem, are the deadliest primary brain cancer in children. Biopsy for pathology plus radiotherapy remains the current standard-of-care treatment that is minimal effective. Thus, the median overall survival after diagnosis is just 10 months. Recent studies have identified a …

Accepts healthy volunteers
  • 0 views
  • 20 Jul, 2022
  • 1 location
Vaccine Therapy in Treating Patients With Metastatic Solid Tumors

This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies and peptides combined with tumor

hormone therapy
tumor cells
serum bilirubin
epidermal growth factor
erbb2
  • 37 views
  • 03 Nov, 2021
  • 1 location
DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection

This phase I trial studies the side effects and best dose of deoxyribonucleic acid (DNA) vaccine therapy in treating patients with hepatitis C virus (HCV) infection that persists or

  • 4 views
  • 08 Nov, 2020
  • 3 locations
Vaccine Therapy With or Without Imiquimod in Treating Patients With Grade 3 Cervical Intraepithelial Neoplasia

immune system in different ways and stop tumor cells from growing. Applying topical imiquimod to the cervix may be an effective treatment for cervical intraepithelial neoplasia. Giving vaccine therapy

human papilloma virus vaccine
myocardial infarction
primary cancer
tumor cells
heart failure
  • 55 views
  • 25 Jul, 2022
  • 1 location
Persistence and Long-Term Protection of Vi Antibodies Induced by Vi-DT Conjugate Vaccines in Indonesian

Vi-DT Typhoid vaccine is a novel vaccine. This study will be done to know the long-term protection and persistent antibody by measured the antibody titer after 2,3,4 and 5 years after immunization.

conjugate vaccine
  • 0 views
  • 30 Jul, 2021
  • 2 locations