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Found 69 clinical trials
Featured trial
  • 157 views
  • 08 Nov, 2020
  • 1 location
Featured trial
  • 512 views
  • 08 Nov, 2020
  • 1 location
A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis

The reason for this study is to see if the study drug baricitinib given orally is safe and effective in participants with active juvenile idiopathic arthritis (JIA)-associated uveitis or chronic

anterior uveitis
eye drops
corticosteroid therapy
steroid therapy
ly3009104
  • 23 views
  • 10 Jul, 2022
  • 24 locations
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial (ADVISE)

immunosuppression. Based upon preliminary data, adalimumab, a fully-human, anti-TNF-α monoclonal antibody, now US FDA-approved for uveitis treatment, may be a superior corticosteroid-sparing agent than conventional

tacrolimus
cyclosporine
small molecule
prednisone
monoclonal antibodies
  • 140 views
  • 14 Jul, 2022
  • 19 locations
Adalimumab Plus Methotrexate for the Treatment of Pediatric Uveitis

The aim of this study is to determine the efficacy and safety of ADA plus MTX for the treatment in non-infectious pediatric panuveitis.

panuveitis
methotrexate
adalimumab
  • 0 views
  • 09 Jan, 2022
  • 1 location
Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis

clinical studies including healthy subjects and patients with psoriasis and psoriatic arthritis and is currently being studied in uveitis, axial spondyloarthritis and hidradenitis suppurativa. This study

angiography
corticosteroids
retinal vascular
fluorescein angiography
prednisone
  • 11 views
  • 10 Aug, 2022
  • 5 locations
Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis

A study to evaluate the safety and efficacy of YUTIQ® 0.18 mg intravitreal implant for the management of chronic non-infectious posterior segment uveitis (intraocular inflammation) that has

fluocinolone acetonide
fluocinolone acetonide intravitreal implant
panuveitis
macular edema
  • 0 views
  • 15 Jun, 2022
  • 1 location
Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes (STACCATO)

to blindness. In immunocompetent patients, however, CMV can cause recurrent inflammation in the front of the eye (anterior uveitis). CMV anterior uveitis produces complications including pain

  • 18 views
  • 24 Jul, 2022
  • 1 location
A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU) (USTEKINISU)

decades, uveitis and the related intraocular inflammation are comparable to diabetes or macular degeneration as a cause of lost quality-adjusted life years due to visual morbidity, and as such are a

  • 32 views
  • 15 Feb, 2022
  • 3 locations