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Found 184 clinical trials
Uterine Transplant for Women With Absolute Uterine Factor Infertility (AUFI)

Absolute Uterine Factor Infertility (AUFI) is due to congenital or surgical absence of a uterus or the presence of a nonfunctional uterus. Until 2014, the only option for women affected by

  • 7 views
  • 10 Jul, 2022
  • 1 location
AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma

This research study is studying an investigational drug as a possible treatment for uterine cancer. The drug involved in this study is: -AZD1775

neutrophil count
carcinoma
measurable disease
carcinosarcoma
metastasis
  • 20 views
  • 04 Oct, 2022
  • 1 location
Radiofrequency Ablation of Adenomyosis

To observe the effects of radiofrequency ablation on adenomyosis through the pathological analysis of treated tissue that has been removed during planned hysterectomy.

fibroids
probe
adenomyosis
  • 2 views
  • 30 Jul, 2023
  • 1 location
[18F]FES PET/.CT in Uterine Cancer

Women with known or suspected recurrent or metastatic uterine cancer may be eligible for this study. Patients may participate in this study if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. [18F]fluoroestradiol (FES) PET/CT imaging …

  • 0 views
  • 16 Sep, 2023
  • 1 location
Window of Opportunity Pilot Study of Pembrolizumab in Obesity-driven Endometrial Cancer

Programmed cell death 1 (PD-1) inhibitor treatment may benefit patients with endometrial cancer (EC) based on the following observations: 1) an overwhelming presence of PD-1 in ECs; 2) the well-known effect of obesity which activates pro-inflammatory white blood cells and promotes the development of ECs; and 3) the high prevalence …

adjuvant therapy
carboplatin
uterine disease
hysterectomy
formalin-fixed paraffin-embedded
  • 0 views
  • 14 Oct, 2022
  • 1 location
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse (PREMIER)

The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.

  • 0 views
  • 29 Jul, 2023
  • 4 locations
Effect of Addition of Steroids on Duration of Analgesia

The purpose of the study is to investigate the differences in post-procedural pain scores and narcotic use among patients who receive a Superior Hypogastric Nerve Block (SHNB) with and without corticosteroid performed as part of the Uterine Artery Embolization (UAE) procedure.

narcotic use
embolisation
embolization of uterine artery
uterine fibroid
leiomyoma
  • 35 views
  • 10 Apr, 2022
  • 1 location
Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

Patients who seek medication abortion early in pregnancy may have an ultrasound that does not show a pregnancy in the uterus. This is known as a "pregnancy of unknown location". These patients

Accepts healthy volunteers
  • 0 views
  • 12 Sep, 2023
Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

Primary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. Second end points: To analyze the appearances of side-effects.

levonorgestrel
progesterone
hyperplasia
endometrial hyperplasia
mirena
  • 49 views
  • 28 Feb, 2022
  • 1 location
Fertility Sparing Management of EndomeTrial Cancer and Hyperplasia

This study protocol evaluates the use of hysteroscopic endomyometrial resection in women diagnosed with atypical endometrial hyperplasia or grade I endometrial cancer who have not responded to anti-hormone therapy. Patients in this study wish to preserve fertility.

progesterone
atypical endometrial hyperplasia
progestin
hyperplasia
cancer
  • 2 views
  • 30 Oct, 2021
  • 1 location