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Found 10 clinical trials
A Cluster Randomized Trial of Labor Induction With Oral Versus Vaginal Misoprostol

This study will compare vaginal and oral misoprostol, to determine whether a vaginal misoprostol regimen achieves a higher vaginal delivery rate in a real-world, high-volume setting, and whether this regimen reduces time and oxytocin need on a high-volume Labor and Delivery unit at Parkland Hospital. Our primary hypothesis is that …

induction of labor
oxytocin
misoprostol
prostaglandin
prenatal
  • 35 views
  • 15 Oct, 2022
  • 1 location
Prevention of Epilepsy by Reducing Neonatal Encephalopathy (PREVENT)

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

electroencephalogram
  • 0 views
  • 07 Jun, 2022
  • 3 locations
Study of Fetoscopic Repair of Myelomeningocele in Fetuses With Isolated Spina Bifida

of incision increases the risk of uterine rupture and requires that all future deliveries are by cesarean section. The use of the minimally invasive fetoscopic surgical technique may also lower the

fetoscopy
fetal spina bifida
uterine rupture
open repair
prenatal
  • 41 views
  • 23 Oct, 2022
  • 1 location
Carboprost (Hemabate) for Fibroid Resection

The purpose of this research study is to determine if low-dose (i.e., a fraction of what is commonly used) carboprost (Hemabate) helps facilitate fibroid removal (myomectomy).

gynecologic surgery
  • 0 views
  • 07 Oct, 2022
  • 1 location
Hand Forceps vs. Conventional One-hand Technique for Fetal Head Extraction During Cesarean Section (Hand forceps)

The aim of the study is to assess the efficacy and safety of an innovative two-hand (hand forceps) fetal head extraction technique during the transverse cesarean sections (LTCS) by comparing with the conventional one-hand technique used worldwide for centuries. The primary research question of the study is whether two-hand fetal …

cesarean section
  • 0 views
  • 27 Apr, 2022
  • 1 location
COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER)

growth restriction, postpartum hemorrhage, fetal distress, uterine rupture, placenta previa, chorioamnionitis, Caesarean delivery, COVID-19), neonatal outcomes (major congenital malformations, low birth

Accepts healthy volunteers
  • 0 views
  • 03 May, 2022
  • 1 location
Molecular Screening Method for Preeclampsia (PREMOM)

Preeclampsia (PE) is a major obstetric complication with short- and long-term consequences for the mother and the fetus. Early screening tools to reduce its mortality and morbidity, as well as to prevent the life-threatening consequences are needed. Thus, the detection of women at risk of suffering PE is key to …

  • 10 views
  • 06 Nov, 2021
  • 18 locations
A Prospective Study of the Impact of Uterine Manipulator on Oncological Outcome in Endometrial Cancer Surgery in Early-stage: Pro MUCEI Study (proMUCEI)

The uterine manipulator is a device commonly used in minimally invasive hysterectomy surgery for endometrial cancer. However, without substantial evidence to support its use, surgeons are required to make decisions about its use based only on their personal choice and surgical experience. A retrospective study demonstrated how uterine manipulator use …

hysterectomy
cancer
cancer surgery
surgery for endometrial cancer
uterine disease
  • 0 views
  • 15 Oct, 2022
  • 1 location
General Drug Use-results Survey on PROPESS Vaginal Inserts in Treatment for Initiation of Cervical Ripening in Patients at Term (From 37 Completed Weeks of Gestation)

safety specification include: uterine hypercontractions and associated foetal distress, uterine rupture, cervical laceration, amniotic fluid embolism, and foetal distress.

  • 0 views
  • 15 Jul, 2022
  • 1 location
Caesarean Section and Intracytoplasmic Sperm Injection (ICSI) Outcome

Although Caesarean section (CS) is often a necessary surgical intervention, it may also be associated with an increased risk of short- and long-term sequelae. It was thought that CS may increase the risk of female subfertility or even infertility. In assisted reproductive technology (ART) cycles, the process of implantation is …

ovarian hyperstimulation syndrome
intracytoplasmic sperm injection
ovarian hyperstimulation
estrogen
estradiol
  • 0 views
  • 07 Oct, 2022
  • 1 location