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Found 50 clinical trials
Pilot Trial of Ustekinumab for Primary Sj gren's Syndrome

This pilot study will make a preliminary determination of the safety of ustekinumab in patients with Primary Sjogren's Syndrome (PSS) and assess the response of systemic measures of inflammation

  • 0 views
  • 15 Mar, 2021
  • 1 location
A Study of Ustekinumab in Participants With Takayasu Arteritis (TAK)

The purpose of this study is to evaluate the efficacy of ustekinumab compared to placebo, in combination with oral glucocorticoid (GC) taper regimen, in participants with relapsing Takayasu

  • 0 views
  • 16 Sep, 2021
  • 28 locations
Clinical Phase II/III Trial of Ustekinumab to Treat Type 1 Diabetes (UST1D2)

insulin injections, blood glucose (sugar) control is imperfect and leads to many health complications and a shortened life span. Our pilot study (NCT02117765) has informed us that Ustekinumab is safe in

hypoglycaemic
type 1 diabetes mellitus
hypoglycemic agents
insulin
c-peptide
  • 0 views
  • 19 Jul, 2021
  • 2 locations
Ustekinumab for the Prevention of Acute Graft Versus Host Disease After Unrelated Donor Hematopoietic Cell Transplant

This phase II trial studies how well ustekinumab works in preventing acute graft versus host disease after unrelated donor hematopoietic cell transplant. Sometimes the transplanted cells from a

cell transplantation
graft versus host disease
carbon monoxide
ejection fraction
mobilized
  • 0 views
  • 17 Sep, 2021
  • 4 locations
Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients With Leukocyte Adhesion Deficiency Type 1 (LAD1) Who Have Inflammatory Pathology

before adulthood. Researchers want to see if a drug called ustekinumab helps people with LAD1. Objective To study the safety and tolerability of ustekinumab in

  • 21 views
  • 19 Aug, 2021
  • 1 location
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNF -Inhibitor Treatment

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNF-inhibitor treatment

arthritis
ustekinumab
rheumatoid factor
tumor necrosis factor
dactylitis
  • 0 views
  • 21 Jul, 2021
  • 27 locations
A Study to Compare SB17 (Proposed Ustekinumab Biosimilar) to Stelara in Subject With Moderate to Severe Plaque Psoriasis

This is a randomised, double-blind, multicentre clinical study to evaluate the efficacy, safety, tolerability, PK, and immunogenicity of SB17 compared to Stelara in subjects with moderate to severe plaque psoriasis.

arthritis
ustekinumab
plaque psoriasis
phototherapy
systemic therapy
  • 0 views
  • 27 Jul, 2021
  • 2 locations
An Open-Label Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

and possibly a maintenance treatment using Ustekinumab. Objectives To see if vorinostat is safe for people with moderate-to-severe CD. To see if it is safe for

mesalamine
natalizumab
tumor necrosis factor alpha
tumor necrosis factor
antibiotics
  • 53 views
  • 23 Jul, 2021
  • 1 location
An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With Ichthyoses

higher) and adults with ichthyotic disorders with ustekinumab in an open-label trial to serially assess clinical response to and safety of ustekinumab for this group of disorders.

  • 0 views
  • 16 Apr, 2021
  • 1 location
TNF and IL23 Blocking Agents Gene Expression Ratios in the Psoriatic Arthritis Synovium_(TIGERS) Study

This study compare the genomics profiles in synovial biopsies obtained prior to, and 24 weeks after a biologic disease modifying anti-rheumatic drugs (DMARDs)(Adalimumab, Ustekinumab, Guselkumab

arthritis
rheumatic diseases
tumor necrosis factor
human chorionic gonadotrophin
biological drug
  • 1 views
  • 25 Mar, 2021
  • 2 locations