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Found 50 clinical trials
Featured trial
Acne, psoriasis, atopic dermatitis

Acne, psoriasis, atopic dermatitis

  • 2006 views
  • 25 Mar, 2021
  • 1 location
Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis (ULTRA)

that exists during GCA. Ustekinumab, which is a monoclonal antibody blocking the subunit common to IL-12 and IL-23 (p40), blocks the Th1 and Th17 responses, and could therefore be an excellent

  • 0 views
  • 26 Apr, 2022
  • 1 location
Stelara fOr ChRonic AntibioTic rEfractory pouchitiS

To evaluate the efficacy and safety of ustekinumab in the treatment of chronic antibiotic refractory and relapsing pouchitis.

  • 14 views
  • 06 May, 2021
  • 2 locations
A Multicenter Phase 2 Single-arm Proof-of-concept Trial to Assess the Efficacy and Safety of Ustekinumab in Association With Prednisone for the Treatment of Non-infectious Severe Uveitis (NISU) (USTEKINISU)

). Ustekinumab, a humanized anti-p40 monoclonal antibody, is able to target both IL-12 and IL-23 pathways, thus disrupting Th1 and Th17 immune responses. Decreasing the dose as well as the duration of

  • 24 views
  • 15 Feb, 2022
  • 3 locations
A Study to Test Whether BI 706321 Combined With Ustekinumab Helps People With Crohn's Disease

This study is open to adults, aged 18-75 years, with moderate to severe Crohn's disease. The purpose of this study is to find out whether BI 706321 combined with ustekinumab helps people

crohn's disease
azathioprine
methotrexate
ulceration
tumor necrosis factor
  • 0 views
  • 12 May, 2022
  • 27 locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC) (UNIFI Jr)

The purpose of this study is to evaluate: a) the efficacy of ustekinumab dosing in inducing clinical remission, b) safety profile of ustekinumab, and c) ustekinumab exposure (pharmacokinetics

endoscopy
remission
  • 0 views
  • 15 May, 2022
  • 45 locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease (UNITI Jr)

The purpose of this study is to evaluate the efficacy of ustekinumab dosing in inducing clinical remission (Global) and in maintaining clinical remission (US); to evaluate the safety profile and

crohn's disease
pediatric onset crohn's disease
endoscopy
ulceration
ileocolitis
  • 0 views
  • 09 May, 2022
  • 43 locations
  • 0 views
  • 22 Dec, 2021
  • 60 locations
A Study to Evaluate Efficacy and Safety of Ustekinumab Re-induction Therapy in Participants With Moderately to Severely Active Crohn's Disease (POWER)

The primary purpose of this study is to evaluate the efficacy and safety of a single intravenous (IV) re-induction dose of approximately 6 milligram per kilogram (mg/kg) ustekinumab in

crohn's disease
azathioprine
methotrexate
antibiotics
ileocolitis
  • 82 views
  • 11 May, 2022
  • 67 locations
Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. This study will evaluate how well risankizumab works compared to ustekinumab. This

crohn's disease
abdominal pain
ustekinumab
tumour necrosis
risankizumab
  • 419 views
  • 16 May, 2022
  • 284 locations