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Found 68 clinical trials
Vasculitis Pregnancy Registry

The purpose of this study is to learn about the experience of women with vasculitis who become pregnant. In particular, the study will consist of several online surveys to assess each woman's vasculitis severity and pregnancy-related experiences, and pregnancy outcomes.

wegener's granulomatosis
churg-strauss syndrome
takayasu's arteritis
behcet's disease
granulomatosis
  • 120 views
  • 24 Jan, 2021
  • 1 location
Study of Mast Cell Precursors

This study will investigate mast cell precursors that circulate in the blood. In a group of diseases collectively known as mastocytosis, mast cells accumulate in abnormal amounts in the skin, lymphoid tissues, bone marrow, liver and spleen. Some forms of mastocytosis have a generally good prognosis; for others, the prognosis …

blood test
kidney function tests
  • 89 views
  • 07 Mar, 2021
  • 1 location
Host Response to Infection and Treatment in Filarial Diseases

site is monitored for swelling or hives in the next 48 hours. Leukapheresis (only on patients 21 or older ) to collect quantities of white blood cells. Whole blood is collected through a

leukapheresis
heart disease
ivermectin
swelling
blindness
  • 20 views
  • 22 Feb, 2021
  • 1 location
Opioid-Redox Study

caused by the effects of opioids are urticaria, dermatitis, and pruritus. Renal and urinary disorders may develop as urinary retention and ureteral spasm. Rarely can occur disorders of the immune system

laxatives
oxycodone
diabetes
nausea
opioid
  • 0 views
  • 24 Jan, 2021
  • 1 location
Biomarker for Hereditary AngioEdema Disease

International, multicenter, observational, longitudinal monitoring study to identify, validate and/or monitor Mass Spectrometry (MS)-based biomarker/s for Hereditary Angioedeme (HAE) disease and to test the clinical robustness, specificity, and predictive value of theese biomarker/s

angioedema
  • 290 views
  • 07 Mar, 2021
  • 13 locations
Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

This study evaluates the efficacy of orally administered PHA-022121 for the acute treatment of attacks in patients with hereditary angioedema (HAE). Eligible subjects are randomized to one of three single doses of PHA-022121 and placebo. The study will compare symptom relief (skin pain, skin swelling, abdominal pain) during HAE attacks …

  • 0 views
  • 14 Feb, 2021
  • 5 locations
Patient Registry to Evaluate the Real-world Safety of Ruconest

This is a prospective, real-world, observational patient registry for patients with HAE who are receiving treatment with Ruconest for HAE.

recombinant human c1 inhibitor
ruconest
c1 inhibitor (human)
  • 64 views
  • 23 Jan, 2021
  • 1 location
Firazyr Patient Registry (Icatibant Outcome Survey - IOS)

The Icatibant Outcome Survey (IOS) is a prospective, observational disease registry designed to document the routine clinical outcomes over time in participants with angioedema treated with Firazyr (icatibant) and/or Cinryze (C1 inhibitor [human]) in countries where it is currently approved. The data collected will be used to evaluate the safety …

angioedema
c1 inhibitor (human)
icatibant
cinryze
  • 294 views
  • 25 Jan, 2021
  • 107 locations
C1 Inhibitor Registry in the Treatment of Hereditary Angioedema (HAE) Attacks

This is a non-interventional treatment Registry of Hereditary Angioedema (HAE) patients treated with C1 inhibitor, either plasma-derived (pdC1INH) or the recombinant human form (rhC1INH / Ruconest), to observe adverse events and insufficient efficacy, and to assess the immunological profile following single and repeated treatment with Ruconest.

angioedema
c1 inhibitor (human)
ruconest
  • 158 views
  • 25 Jan, 2021
  • 19 locations
Study to Evaluate the Real-world Effectiveness of Lanadelumab in Participants With Hereditary Angioedema (HAE)

This observational, prospective study aims to evaluate the real-world effectiveness of lanadelumab in participants with hereditary angioedema (HAE). Participant-reported attack diaries and patient-reported outcomes (PROs) as well as physician assessments at standard of care (SoC) visits will be used to describe HAE attack rates, treatment patterns, healthcare utilization and participant …

angioedema
  • 76 views
  • 26 Jan, 2021
  • 31 locations