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Found 70 clinical trials
Assessment of Suppression of Cutaneous Allergic Responses and Pruritus by Topical Doxycycline

Investigators will study the effects of topical doxycycline on cutaneous allergic early and late phase responses by determining allergen skin responses in each subject after a single application to allergen induced allergic swelling of 2% doxycycline in emollient.

asthma
aquaphor
allergen
swelling
  • 102 views
  • 23 Jan, 2021
  • 1 location
  • 4 views
  • 27 Jan, 2021
  • 2 locations
Efficacy and Safety of Lanadelumab for Prevention Against Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

The purpose of this study is to evaluate the safety and efficacy of repeated subcutaneous (SC) administrations of lanadelumab in preventing angioedema attacks in adolescents and adults with non-histaminergic angioedema with normal C1-INH.

wheals
bilateral oophorectomy
cetirizine
serum pregnancy test
angioedema
  • 132 views
  • 26 Jan, 2021
  • 15 locations
Mepolizumab for the Treatment of Chronic Spontaneous Urticaria

This is an exploratory study designed to generate preliminary data in evaluating the efficacy of Nucala in the treatment of chronic spontaneous urticaria.

urticaria
antihistamine therapy
antihistamines
nucala
  • 0 views
  • 24 Jan, 2021
  • 1 location
Study of Mechanism of Action of Ligelizumab (QGE031) in Patients With Chronic Urticaria

The purpose of the study is to investigate the mechanism of action for ligelizumab (QGE031) treatment in patients with chronic urticaria. The study has two parts. The study population

cindu
electrocardiogram
ligelizumab
a 12
urticaria
  • 0 views
  • 25 Jan, 2021
  • 1 location
Mepolizumab in Episodic Angioedema With Eosinophilia

Background Gleich syndrome is also called episodic angioedema with eosinophilia (EAE). People with EAE have episodes of swelling. They may also have itching, hives

  • 0 views
  • 02 Feb, 2021
  • 1 location
A Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria

This is a study to determine the safety of multiple doses of CDX-0159 in patients with Chronic Spontaneous Urticaria.

  • 0 views
  • 26 Jan, 2021
  • 5 locations
A Safety and Efficacy Study of Ligelizumab in the Treatment of CSU in Japanese Patients Inadequately Controlled With H1- Antihistamines

The purpose of this study is to evaluate the safety and efficacy of ligelizumab in adult Japanese subjects with CSU, who remain symptomatic despite treatment with H1-antihistamines (AHs) at locally approved doses. The study population will consist of approximately 65 male and female subjects aged 18 years who have been …

urticaria
ligelizumab
a 12
antihistamines
  • 4 views
  • 26 Jan, 2021
  • 10 locations
A Single Dose Study of the Safety Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Urticaria or Symptomatic Dermographism

This is a study to determine the safety of CDX-0159 in patients with Cold Contact Urticaria or Symptomatic Dermographism.

  • 0 views
  • 15 Feb, 2021
  • 1 location
A Study to Evaluate Safety Tolerability Pharmacokinetics and Pharmacodynamics of UCB8600 in Healthy Participants Atopic Participants and Chronic Spontaneous Urticaria Participants

The purpose of the study is to assess safety, tolerability and pharmacokinetics (PK) of oral UCB8600.

atopic
electrocardiogram
urticaria
serum immunoglobulin e
12-lead electrocardiogram
  • 0 views
  • 27 Jan, 2021
  • 1 location