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Found 762 clinical trials
Featured trial
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

This is a multicenter, open-label parallel-group to evaluate single oral doses of INCB000928 in participants with varying level of renal function or impairment.

Accepts healthy volunteers
renal function
body mass index
  • 0 views
  • 20 Jul, 2022
  • 4 locations
Featured trial
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

. Researchers want to see if this therapy fights kidney cancer cells. Metastatic renal cell carcinoma (RCC) is an incurable condition. Current therapy for this disease consists of the serial administration

clear cell carcinoma
renal cell cancer
carcinoma
clear cell renal cell carcinoma
metastatic cancer
  • 210 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Double-Blind, Placebo-Controlled, Parallel Design, Phase 2 Study to Assess Clinical Activity and Safety of Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence

urinary tract disorders, as both testosterone and its more potent metabolite, dihydrotestosterone, have anabolic effects on muscle. Clinical trial NCT03241342, G201002.

  • 498 views
  • 02 Sep, 2021
  • 1 location
Featured trial
AREN03B2: Renal Tumors Classification, Biology, and Banking Study

AREN03B2: Renal Tumors Classification, Biology, and Banking Study

  • 106 views
  • 08 Nov, 2020
  • 1 location
Featured trial
RENAL AID: Repository of Novel Analytes Leading to Autoimmune, Inflammatory, and Diabetic Nephropathies

RENAL AID: Repository of Novel Analytes Leading to Autoimmune, Inflammatory, and Diabetic Nephropathies

  • 218 views
  • 25 Mar, 2021
  • 1 location
Featured trial
A Phase 1b, Dose-escalation Study of Pexa-Vec (Thymidine Kinase-Deactivated Vaccinia Virus Plus GM-CSF) in Combination With REGN2810 (Anti-PD-1) in Patients With Metastatic or Unresectable Renal Cell Carcinoma (RCC)

This is a Phase 1b, open-label, multi-center, dose-escalation trial of Pexa-Vec plus REGN2810 in patients with metastatic or unresectable renal cell carcinoma (RCC). The trial consists of a

renal cell cancer
clear cell renal cell carcinoma
metastatic renal cell carcinoma
systemic therapy
measurable disease
  • 2 views
  • 23 Nov, 2020
  • 3 locations
Featured trial
A Phase 1/1b Study of Sitravatinib in Combination with Nivolumab and Ipilimumab in Patients with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies

Study 516-008 is an open-label Phase 1 dose escalation/Phase 1b dose expansion study evaluating the safety and tolerability, clinical activity, and PK of sitravatinib in combination with nivolumab and ipilimumab for the treatment of ccRCC and potentially other solid tumor types. Sitravatinib is a spectrum-selective receptor tyrosine kinase (RTK) inhibitor …

systemic therapy
carcinoma
nivolumab
VEGFR2
monoclonal antibodies
  • 57 views
  • 15 Sep, 2020
  • 1 location
Featured trial
VastBiome: The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors

The microbiome has the potential to serve as a robust biomarker of clinical response to immunotherapy. Additionally, microbial manipulation, through diet, exercise, prebiotics, probiotics, or microbially-derived metabolites, may prove to be beneficial in promoting anti-tumor immune responses. However, large prospective studies in humans with longitudinal sample collection and standardized methods …

cancer
programmed cell death 1 ligand 1
targeted therapy
cancer chemotherapy
  • 0 views
  • 28 Feb, 2022
  • 1 location