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Found 17 clinical trials
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology

This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim system. Subjects from both groups will immediately start with therapy. The primary endpoint is a 50% reduction in number of incontinence episodes associated with …

  • 27 Jan, 2021
  • 16 locations
Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Overactive Bladder

Prospective, multi-center, single-arm, seamless phase-pivotal study conducted in participants diagnosed with UUI who have failed or could not tolerate more conservative treatment. The trial will be conducted in two phases. Objective of Phase I: To assess the utilization of the system during the Sacral Nerve Stimulation (SNS) trial period and …

  • 25 Jan, 2021
  • 10 locations
Bladder and TranscUtaneous Tibial Nerve Stimulation for nEurogenic Lower Urinary Tract Dysfunction

Many patients with neurological diseases suffer from neurogenic lower urinary tract dysfunction (NLUTD), which often severely impairs quality of life, due to urinary urgency with or without

  • 25 Jan, 2021
  • 6 locations
Inflammation in Women With Urgency Urinary Incontinence Treated With Anticholinergics

Urinary incontinence (UI) is a very common condition affecting women of all ages. The objective of this pilot study is to better understand the urinary microbiome and associated inflammatory markers in blood and urine in women with urgency UI. The study will assess how inflammation may affect response to standard …

anticholinergic agents
urinary urgency
  • 28 Jan, 2021
A Group-Based Therapeutic Yoga Intervention for Urinary Incontinence in Ambulatory Older Women

The investigators will conduct a randomized controlled trial to evaluate the efficacy of a group-based yoga intervention to decrease the frequency and impact of urinary incontinence in ambulatory middle-aged and older women and explore potential mediators of improvement in outcomes. Women aged 45 years and older who report daily or …

  • 25 Jan, 2021
  • 2 locations
Clinical Efficacy of Changing the InterStim Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome

Purpose To demonstrate better symptoms control (pain, urinary urgency and frequency) with sacral neuromodulation (SNM) in patients with interstitial cystitis

urinary urgency
female sexual dysfunction
chronic interstitial cystitis
bladder pain
  • 08 Nov, 2020
  • 1 location
Laser Vaginal Treatment for GSM

vaginal dryness, itching, discomfort, malodour, painful intercourse and may have urinary urgency, irritation, bladder/urethral pain and recurring bladder infections. First-line therapies include vaginal

  • 26 Jan, 2021
  • 1 location
Noninvasive Spinal Cord Stimulation for Neurogenic and Idiopathic Overactive Bladder

Overactive bladder (OAB) affects 12-30% of the world's population. The accompanying urinary urgency, urinary frequency and incontinence can impair the ability to work, interact in social

overactive detrusor
urinary urgency
botulinum toxin
overactive bladder
  • 24 Jan, 2021
  • 1 location
Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease

likely due to the combination of urinary urgency and impaired mobility (and falls are a leading cause of mortality in PD), for spouse/caregiver stress due to decreased mutuality in the relationship, and

urinary symptoms
urinary urgency
bladder symptoms
movement disorder
  • 27 Jan, 2021
  • 4 locations
Cystoprostatectomy Versus Radiotherapy Combined With ADT for the Treatment of cT4 Prostate Cancer With Bladder Invasion

cancer with bladder invasion patients, symptoms of hematuria, urinary urgency, bladder outlet and ureteral obstruction, and pelvic pain led to a poor quality of life. Radical prostatectomy is

antiandrogen therapy
external beam radiotherapy
prostate specific antigen
adenocarcinoma of prostate
  • 22 Jan, 2021
  • 1 location