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Found 20 clinical trials
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A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 25 Mar, 2021
  • 1 location
Bioengineered Collagen Implant for Urethral Stricture Repair

urethroplasty of distal urethral strictures.

  • 22 Jul, 2022
  • 1 location
Nanofat Grafting in Male and Female Subjects Affected by Urethral Strictures (NFUS)

adipocytes (microfat, lipofilling, macrofat), such as the formation of deposits, granulomas, oily cysts, keloids. Investigators aim to evaluate the use of nanofat grafting in the treatment in urethral

  • 24 Jul, 2022
  • 1 location
DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures (DoVe)

For bulbar urethral strictures, it remains unclear whether ventral onlay graft urethroplasty is non-inferior to dorsal onlay graft urethroplasty in terms of patency rates.

  • 22 Mar, 2022
  • 1 location
Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures

In this study the investigators investigate the feasibility and therapeutic potential of free autologous fat grafting combined to direct visual urethrotomy (DVIU) in the treatment of urethral

  • 04 Jun, 2021
  • 1 location
Multi-stage Urethroplasty With Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage

The principal aim of this pilot study is to directly compare both approaches and analyze the failure rate after one year of follow-up. These data will serve as the basis to design a larger phase II or III trial in the future with failure rate as the primary end-point. Other …

  • 25 Jul, 2021
  • 1 location
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters (STREAM)

Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 55 years of age.

  • 04 Jun, 2022
  • 1 location
The Nanofat Regenerative Surgery for Management of Genital Lichen Sclerosus in Male and Female Patients (LSNanofat)

Regenerative surgery is an emerging multidisciplinary field actually based on derived adipose tissue. Autologous fat grafting was first described by Neuber in 1893 and since then it has developed over the next century. The initial goal of fat grafting was to treat volume losses created by disease or trauma. Further …

Accepts healthy volunteers
  • 29 Jul, 2022
  • 1 location
Clostridium Histolyticum Collagenase Injection Treatment for Urethral Disease: a Prospective, Single-center, Open-label Study

The purpose of this study is to assess the efficacy of clostridium histolyticum collagenase (XIAFLEX®) in treating urethral strictures.

  • 23 Sep, 2022
  • 1 location
Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty

The investigator's study aims to see if an enhanced recovery regimen of pain medications before and during surgery will decrease the use and risk of opioid pain medications as well as improve pain control in anterior urethroplasty patients. Participants will be randomized to one of two pain regimens (enhanced recovery …

ibuprofen 800 mg
  • 07 Feb, 2022
  • 1 location