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Found 143 clinical trials
Mandibular Reconstruction With Axially Vascularised Bone Substitutes

Mandibular reconstruction is necessary following trauma, tumour resections and extensive infections resulting in severe defects of the mandibular arch. For reconstructing large and recurrent defects, the vascularized free flaps are currently regarded as the gold standard. The use of these flaps, however, presents several major inconveniences. Although regenerative medicine in …

  • 144 views
  • 05 Jun, 2022
  • 1 location
Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication

. 6-8 weeks after treatment, the subjects will re-take the 13C-urea breath test. Calculate the eradication rates, adverse reaction rates, patient compliance and cost-effectiveness index of each group

  • 0 views
  • 29 Jun, 2022
  • 4 locations
PSMA-PET: Deep Radiomic Biomarkers of Progression and Response Prediction in Prostate Cancer

castration resistance. [18F]DCFPyL is a promising high-sensitivity second generation PSMA-targeted urea-based PET probe. Studies employing second-generation PSMA PET/CT imaging in men with biochemical

aggressiveness
prostate cancer metastatic
pet/ct scan
metastatic prostate cancer
metastasis
  • 0 views
  • 16 Aug, 2021
  • 1 location
Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication

Up to know, three is few large-scale, randomized study prospectively and simultaneously comparing the efficacy, adverse effects and patient compliance of high-dose dual therapy (HDDT) with or without bismuth versus amoxicillin-metronidazole bismuth quadruple therapy (AM-BQT) as first-line regimens for H. pylori eradication. The aims of this study are: to compare …

rabeprazole
metronidazole
peptic ulcer
amoxicillin
gastritis
  • 15 views
  • 23 Mar, 2022
  • 1 location
HELicobacter Pylori Screening to Prevent Gastrointestinal Bleeding in MI Patients

Background: Potent antithrombotic therapy has improved prognosis for patients with acute myocardial infarction (MI) significantly, however, at a price of increased bleeding risk. Helicobacter pylori (H. pylori) infection commonly causes upper gastrointestinal bleeding (UGIB). If systematic screening for H. pylori and subsequent eradication therapy significantly reduces the risk of UGIB …

stroke
myocardial infarction
infarct
heart failure
fasting
  • 0 views
  • 01 Dec, 2021
  • 35 locations
Urea for Chronic Hyponatremia

This study is examining how a dietary supplement called urea can be used to treat low blood sodium level. Low blood sodium level is a common problem and some studies show that many patients with

blood sodium
osmolality
siadh
chronic hyponatremia
  • 0 views
  • 08 Jun, 2022
  • 1 location
Dysregulated Urea-synthesis at Terminal Uremia

This project will examine the dysregulation of the urea cycle in patients with terminal uremia using a validated method named "Functional Hepatic Nitrogen Clearance"

chronic hemodialysis
urea
Accepts healthy volunteers
  • 0 views
  • 22 Oct, 2021
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage (NAT-URE)

. In addition, the correction of hyponatremia is diametrically opposed according to its mechanism: water restriction in the case of SIADH, sodium intake in the event of CSWS. Urea is offered as a

  • 55 views
  • 25 May, 2022
  • 1 location
Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD

This is a study involving a dietary supplement. Patients with argininosuccinate lyase deficiency (ASLD) will be randomly assigned to receive either a nitric oxide dietary supplement or placebo for 24 weeks, and then crossed-over to receive the other treatment for 24 weeks. The investigators will assess the effects of the …

nitric oxide
deficiency
argininosuccinic aciduria
genetic testing
  • 26 views
  • 29 Aug, 2021
  • 1 location
Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders

This is a randomized, controlled, open-label parallel arm study to assess the safety, tolerability, pharmacokinetics and ammonia control, of RAVICTI® as compared to NaPBA in urea cycle disorder

hysterectomy
genetic testing
phenylacetic acid
ravicti
phenylbutyrate
  • 44 views
  • 03 May, 2022
  • 8 locations