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Found 143 clinical trials
[68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients

Glucagon-like peptide-1 receptor (GLP-1R)-targeted PET imaging with 68Ga-labeled compounds is able to provide superior sensitivity and specificity to detect insulinoma, like the widely studied [68Ga]Ga-NOTA-exendin-4. This pilot study was prospectively designed to evaluate the early dynamic distribution of [68Ga]Ga-HBED-CC-exendin-4, a novel radiopharmaceutical targeting GLP-1R, which was compared with [68Ga]Ga-NOTA-exendin-4 in …

  • 1 views
  • 12 Sep, 2021
  • 1 location
Modulation of the Gut-brain Axis by Cranberries: Impact on University Students' Mental Wellbeing (CM)

In this work, the investigators will assess whether cranberry (poly)phenols improve mood disorders including stress, anxiety and depression via the gut-brain axis in university students. The investigators will evaluate whether the effects observed are related to an improvement in gut microbiome diversity and function, and whether the mechanism of action …

Accepts healthy volunteers
  • 0 views
  • 19 Apr, 2022
  • 1 location
Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Fluorouracil is recommended for the topical treatment of multiple actinic or solar keratoses. In the 5% strength, it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites.

  • 0 views
  • 10 May, 2022
  • 6 locations
Feasibility of Low Energy Diet in HFpEF and Type 2 Diabetes (ALLEVIATE)

Open, Single arm intervention, feasibility study

  • 0 views
  • 09 Jun, 2022
  • 1 location
Sulphur Amino Acid Requirements in Adults >60 Years

This study aims to determine the requirements for the sulphur amino acids in adults over the age of 60 years: the total sulphur amino acid requirement as methionine only. Methionine is an essential amino acid. the minimum methionine requirement as methionine in the presence of excess dietary cysteine. It is …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
RandomizEd ClinicAL triaL on the Efficacy and saFety of Incremental Hemodialysis (REAL-LIFE)

Background: The thrice-weekly hemodialysis (HD) regimen is widely accepted as a standard prescription. The concept of incremental dialysis has been established as a possible alternative for patients with preserved diuresis and end-stage renal failure in need of HD. The main problems related to prescription of incremental HD are an arbitrary …

  • 0 views
  • 04 Jun, 2022
  • 1 location
Influence of Dexmedetomidine or Propofol on ICU Delirium

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am after diagnosis of hyperactive or mixed delirium, decreases the duration of delirium. The infusions might have to be repeated …

dexmedetomidine
propofol
  • 0 views
  • 24 Apr, 2022
  • 1 location
Selinexor Treatment for Multiple Myeloma Patients Who Are Refractory to Lenalidomide-containing Therapy.

This is a pilot study evaluating the safety and efficacy of selinexor among multiple myeloma (MM) patients that are refractory to lenalidomide-containing regimens with or without steroids.

  • 0 views
  • 06 May, 2022
  • 1 location
WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?

The trial is a pharmacodynamic study to determine the effect of a novel regimen of aspirin 20 mg BD plus rivaroxaban 2.5 mg BD on haemostasis, fibrin clot dynamics, inflammatory markers, platelet function and arachidonic acid metabolites when compared to standard regimens of aspirin 75 mg OD and aspirin 75 …

  • 0 views
  • 25 Sep, 2021
  • 1 location
Topical Vancomycin Over Sternal Edge in Cardiac Surgery

This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery. Vancomycin paste will be prepared using 2.5 g of vancomycin mixed with 2 ml normal saline. Vancomycin …

  • 0 views
  • 12 Sep, 2021
  • 1 location