Found 12 clinical trials
FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea (FRIEND)
The objective of this study is to determine the effect of low caffeine green tea extract containing 45% epigallocatechin gallate (EGCG) on fibroids and subsequent pregnancy and live births in women seeking fertility treatment. The population will consist of 200 women desirous of conceiving, ages ≥18 to ≤40 years (at …
- 0 views
- 07 Oct, 2022
- 3 locations
In Vitro Fertilisation Versus Intracytoplasmic Sperm Injection in Patients Without Severe Male Factor Infertility (INVICSI)
Over recent decades, the use of intracytoplasmic sperm injection (ICSI) has increased, even among patients without severe male factor infertility. Despite the increasing use, there is no evidence to support that ICSI results in a higher live birth rate compared to conventional in vitro fertilisation (IVF) in cases without severe …
- 922 views
- 04 Oct, 2022
- 1 location
Organic Pollutants in Pelvic Endometriosis
The health toxicity of polycyclic aromatic hydrocarbons (PAHs), present in air and food, generated during energy production and waste incineration, is well known. PAHs can activate the aryl hydrocarbon receptor, which may interact with classic estrogen receptors and modify estrogen-dependent inflammation in endometriosis. There is no data on the hypothetical …
- 0 views
- 12 Apr, 2023
Uterine Scratching in Intra-Uterine Insemination
This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultrasound.
- 48 views
- 07 Oct, 2022
- 1 location
Effects of Intrauterine Administration of Autologous PBMC Modulated With IFNt on Endometrial Cell Populations
The aim of this clinical trial is to investigate the change in endometrial composition during the window of implantation following intrauterine administration of PBMC immunomodulated with IFNt. Patients seeking assisted reproductive therapy will be invited to participate. Two endometrial biopsies will be obtained from each patient during mid-secretory phase of …
- 0 views
- 07 Apr, 2023
- 1 location
Mechanistic Characterization of Uterine Pain (MCUP)
There are limited treatment options for management of dysmenorrhea, and the physiological processes they affect are not completely understood. For example, NSAIDs are effective in reducing menstrual pain in some women by inhibition of prostaglandin synthesis, but whether those effects are mediated by affecting contractility, perfusion, or hypoxemia is unknown. …
- 148 views
- 17 Jun, 2022
- 1 location
Treatment With the Anti-IgE Monoclonal Antibody Omalizumab in Women With Asthma Undergoing Fertility Treatment. - A Proof of Concept Study. (PRO_ART)
The investigators have previously confirmed a clinical hunch that women with asthma have difficulties in becoming pregnant. The investigators found increased time to pregnancy (TTP) in women with asthma compared to non-asthmatic women (55 vs 33 months, p<0.001), furthermore, women with asthma had less successful pregnancies following fertility treatment (39.6 …
- 152 views
- 25 Mar, 2022
Developmental Epidemiological Study of Children Born Through Reproductive Technology (DESCRT)
DESCRT will be a long-term study that both looks back in time, at successful pregnancies, and forward in time at early pregnancy and long-term as these children grow. Currently, there are limited data on the long-term effects of infertility and infertility treatments on children. There are some studies to suggest …
- 273 views
- 02 Mar, 2022
- 1 location
PMA-FERTITHEQUE Biocollection (FERTITHEQUE)
Creation of a patient library in Medically Assisted Procreation to allow the implementation of further research with the following objectives: To identify new relevant biomarkers in patients who will carry a pregnancy to term To better specify or identify new infertility risk factors To identify new relevant biomarkers in patients …
- 0 views
- 03 Apr, 2023
- 1 location
Predicting Endometrial Receptivity for Optimal Reproductive Management (PERFORM)
biopsy material from hyperstimulated (gonadotropin treated) subjects after egg retrieval. If successful, it would provide a new protocol for women with unexplained infertility or those with known
- 316 views
- 04 Oct, 2022
- 1 location
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