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Found 13 clinical trials
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A Trial of TTI-621 in Combination With Doxorubicin in Patients With Leiomyosarcoma

Multi-center, open-label, Phase I/II dose escalation and expansion trial of TTI-621 in patients with unresectable or metastatic high-grade leiomyosarcoma.

cancer chemotherapy
soft tissue sarcoma
liposarcoma
doxorubicin
undifferentiated pleomorphic sarcoma
  • 14 views
  • 09 Dec, 2021
  • 2 locations
None
A Single-arm Open Phase II Study of Chidamide Combined With Toripalimab in Refractory and Advanced Soft-tissue Sarcoma

Soft tissue sarcoma is a relatively rare malignant tumor with an incidence of about 1-2/100,000. The best way to obtain evidence-based medical evidence is to participate in clinical trials with new drugs (especially targeted drugs and immunotherapy). Chidamide, an oral subtype-selective histone deacetylase inhibitor monotherapy was effective on the patients …

liposarcoma
synovial sarcoma
monoclonal antibodies
malignant peripheral nerve sheath tumor
undifferentiated pleomorphic sarcoma
  • 2 views
  • 24 Mar, 2021
  • 1 location
None
Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

This study is being done to find the safest dose of DCC-3014 that can be given with avelumab to participants with advanced or metastatic sarcomas that will not cause serious side effects.

high grade sarcoma
myxofibrosarcoma
cancer chemotherapy
liposarcoma
undifferentiated pleomorphic sarcoma
  • 22 views
  • 06 Jan, 2022
  • 1 location