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Found 38 clinical trials
MASked-unconTrolled hypERtension Management Based on Office BP or on Out-of-office (Ambulatory) BP Measurement (MASTER)

MASTER study is a 4-year prospective, randomized, open-label, blinded-endpoint study (PROBE) comparing 2 management strategies 1) office BP as a guide to treatment, or 2) 24-hour ABP as a guide to treatment. Study objectives are to investigate whether a management strategy based on out-of-office BP (Ambulatory BP monitoring) versus a …

uncontrolled hypertension
antihypertensive drugs
  • 6 views
  • 23 Mar, 2022
  • 1 location
Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe CKD (Clarion-CKD)

adult participants who have stage 3b/4 chronic kidney disease (CKD) (estimated glomerular filtration rate [eGFR] ≥15 to ≤44 mL/min/1.73 m^2) and uncontrolled hypertension (systolic blood pressure (SBP

body mass index
glomerular filtration rate
  • 0 views
  • 14 May, 2022
  • 29 locations
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome (GRACE)

syndrome and concurrent type 2 diabetes mellitus/impaired glucose tolerance and/or uncontrolled hypertension

relacorilant
hypertension
diabetes
  • 198 views
  • 21 Mar, 2022
  • 64 locations
Bridging the Evidence-to-practice Gap

The proposed project will address this evidence-to-practice gap by evaluating the effect of practice facilitation (PF) of the intervention implementation fidelity (primary outcome) and clinical measures at 12 months (secondary outcomes).

hypertensive medication
hypertension
  • 0 views
  • 01 Dec, 2021
  • 1 location
Remote Monitoring and Virtual Collaborative Care For Hypertension Control to Prevent Cognitive Decline Phase II (vCCC 2)

This is a randomized, controlled, pragmatic trial designed as a "type I hybrid effectiveness-implementation trial" that tests a hypertension program integrating a virtual Collaborative Care Clinic (vCCC), home blood pressure monitoring, and telehealth for lowering blood pressure (BP) in two health systems.

raised blood pressure
home blood pressure monitoring
hypertension
  • 0 views
  • 06 Apr, 2022
  • 1 location
Conquering Hypertension in Vietnam: Solutions at Grassroots Level (HY-TREC)

The objectives of the proposed project are to evaluate the implementation and effectiveness of two multi-faceted community and clinic-based strategies on the control of elevated blood pressure (BP) among adults in Vietnam via a cluster-randomized trial design. Sixteen communities will be randomized to either an intervention (8 communities) or comparison …

hypertension
self monitoring
  • 2 views
  • 20 Feb, 2022
  • 1 location
Uptake of Task-Strengthening for Blood Pressure Control

Uptake of a community-based evidence-supported interventions for hypertension control in Ghana are urgently needed to address the cardiovascular disease epidemic and resulting illness, deaths, and societal costs. This study will evaluate the effect of Practice Facilitation on the uptake and maintenance of the evidence-based task-shifting strategies for hypertension control (TASSH) …

cardiovascular disease
hypertension
  • 1 views
  • 07 Apr, 2022
  • 1 location
A Study to Assess the Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of ION904 in Participants With Uncontrolled Hypertension

The purpose of this study is to evaluate the effect of ION904 on plasma angiotensinogen (AGT) in participants with uncontrolled hypertension.

  • 0 views
  • 24 May, 2022
  • 3 locations
Renal Denervation in Chronic Kidney Disease - RDN-CKD Study (RDN-CKD)

RDN-CKD Study is a prospective, randomized (1:1, central randomization), double-blind (unblinded interventionalist and blinded study team at each center), sham controlled, multicenter feasibility study. The purpose of the RDN-CKD Study is to demonstrate that renal denervation (RDN) effectively reduces 24-h ambulatory BP in 80 patients with chronic kidney disease (CKD) …

  • 0 views
  • 21 Mar, 2022
  • 2 locations
Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence

The purpose of this study is to compare the effect of two educational interventions on adherence to blood pressure medications among adults with uncontrolled hypertension.

uncontrolled hypertension
hypertension
local anesthetic
diet, sodium-restricted
KIT
  • 0 views
  • 25 Jan, 2021
  • 1 location