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Found 14 clinical trials
Featured trial
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

anemia studies
aplastic anemia
myelodysplastic syndromes
myelodysplastic syndrome (mds)
  • 57 views
  • 22 Dec, 2020
  • 1 location
Umbilical Cord Blood Transplantation From Unrelated Donors

This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.

chemotherapy regimen
blast crisis
fludarabine
umbilical cord blood transplantation
severe aplastic anemia
  • 80 views
  • 12 Jul, 2022
  • 1 location
Granulocyte Transfusions After Umbilical Cord Blood Transplant

Although most children with leukaemia are cured using drugs (chemotherapy) alone, for some children additional treatments are needed. Stem cell transplant can cure children where chemotherapy and other drugs have failed. In this case, the immune cells of the donor attack the leukaemia cells of the patient. Cord blood collected …

  • 0 views
  • 12 Jul, 2022
  • 1 location
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

This is a treatment guideline for an unrelated umbilical cord blood transplant (UCBT) using a myeloablative preparative regimen for the treatment of hematological diseases, including, but not

lymphoblastic lymphoma
raeb
myelofibrosis
chemotherapy regimen
blast crisis
  • 146 views
  • 25 Feb, 2022
  • 1 location
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

This phase II trial studies how well giving an umbilical cord blood transplant together with cyclophosphamide, fludarabine, and total-body irradiation (TBI) works in treating patients with

lymphoblastic lymphoma
mycophenolate
abnormal cells
raeb
acute biphenotypic leukemia
  • 129 views
  • 07 Oct, 2022
  • 1 location
  • 2 views
  • 07 Mar, 2022
  • 1 location
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective To test if treating people with SAA or MDS with a co-infusion of …

blood test
anemia
neutrophil count
bone marrow transplant
hla-a
  • 12 views
  • 04 Oct, 2022
  • 1 location
Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

This phase II trial studies how well donor umbilical cord blood transplant with ex-vivo expanded cord blood progenitor cells (dilanubicel) works in treating patients with blood cancer. Before

kinase inhibitor
tyrosine
myelodysplastic syndromes
blast crisis
hla-a
  • 10 views
  • 07 Apr, 2023
  • 1 location
Personalized NK Cell Therapy After Chemotherapy and Cord Blood Transplant in Treating Patients With Myelodysplastic Syndrome, Leukemia, Lymphoma or Multiple Myeloma

This phase II clinical trial studies how well personalized natural killer (NK) cell therapy works after chemotherapy and umbilical cord blood transplant in treating patients with myelodysplastic

clofarabine
tyrosine
cellular therapy
acute biphenotypic leukemia
rituximab
  • 58 views
  • 05 Jul, 2022
  • 1 location
Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation

In the United States, thiotepa has been utilized in reduced intensity conditioning regimens for alternative donor courses (double umbilical cord blood transplant (dUCBT) and haplo-identical

myelodysplastic syndromes
blast crisis
remission
hodgkin's disease
fludarabine
  • 12 views
  • 22 Mar, 2022
  • 1 location