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Found 18 clinical trials
Featured trial
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

aplastic anemia
anemia studies
myelodysplastic syndromes
myelodysplastic syndrome (mds)
  • 57 views
  • 22 Dec, 2020
  • 1 location
Umbilical Cord Blood Transplantation From Unrelated Donors

This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.

busulfan
wiskott-aldrich syndrome
multiple myeloma
refractory multiple myeloma
hodgkin's disease
  • 80 views
  • 16 May, 2021
  • 1 location
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

This is a treatment guideline for an unrelated umbilical cord blood transplant (UCBT) using a myeloablative preparative regimen for the treatment of hematological diseases, including, but not

preparative regimen
pancytopenia
imatinib
hypodiploidy
b-cell lymphoma
  • 146 views
  • 25 Feb, 2022
  • 1 location
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

This phase II trial studies how well giving an umbilical cord blood transplant together with cyclophosphamide, fludarabine, and total-body irradiation (TBI) works in treating patients with

imatinib
pancytopenia
blood cell count
acute biphenotypic leukemia
b-cell lymphoma
  • 129 views
  • 23 Jan, 2022
  • 1 location
  • 2 views
  • 07 Mar, 2022
  • 1 location
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

This phase II trial studies how well an umbilical cord blood transplant with added sugar works with chemotherapy and radiation therapy in treating patients with leukemia or lymphoma. Giving

blood cell count
acute biphenotypic leukemia
busulfan
mycophenolate mofetil
acute leukemia
  • 36 views
  • 28 Jan, 2022
  • 1 location
Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

This phase II trial studies how well donor umbilical cord blood transplant with ex-vivo expanded cord blood progenitor cells (NLA101) works in treating patients with blood cancer. Before the

pancytopenia
blood cell count
carbon monoxide
myeloid leukemia
acute leukemia
  • 10 views
  • 12 May, 2022
  • 1 location
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective To test if treating people with SAA or MDS with a co-infusion of …

hla-a
bone marrow transplant
neutrophil count
blood test
stem cell transplantation
  • 12 views
  • 11 May, 2022
  • 1 location
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT (HSCT+RIC)

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT, matched unrelated

  • 22 views
  • 25 Mar, 2022
  • 1 location
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

have evidence of early demyelinating disease in the central nervous system (CNS) who are undergoing standard treatment with unrelated umbilical cord blood transplantation (UCBT). The secondary

sandhoff disease
cortical atrophy
seizure
mps iii
jaundice
  • 199 views
  • 23 Dec, 2021
  • 1 location