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Found 19 clinical trials
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Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

aplastic anemia
myelodysplastic syndromes
myelodysplastic syndrome (mds)
anemia studies
  • 57 views
  • 22 Dec, 2020
  • 1 location
Umbilical Cord Blood Transplantation From Unrelated Donors

This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.

hemolysis
treatment-related aml
aplastic anemia
solid tumour
chemotherapy regimen
  • 80 views
  • 25 Jan, 2021
  • 1 location
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

This is a treatment guideline for an unrelated umbilical cord blood transplant (UCBT) using a myeloablative preparative regimen for the treatment of hematological diseases, including, but not

residual tumor
nodal mass
lymphoblastic lymphoma
chronic myeloid leukemia
minimal residual disease
  • 146 views
  • 26 Jan, 2021
  • 1 location
Umbilical Cord Blood Transplant Cyclophosphamide Fludarabine and Total-Body Irradiation in Treating Patients With Hematologic Disease

This phase II trial studies how well giving an umbilical cord blood transplant together with cyclophosphamide, fludarabine, and total-body irradiation (TBI) works in treating patients with

blood cell count
hla-a
residual disease
residual tumor
nodal mass
  • 125 views
  • 11 Apr, 2021
  • 3 locations
Haploidentical CD34+ Selected Cells Combined With Single Unit Umbilical Cord Blood Transplant for Treatment of High-risk Hematologic Disorders

cord blood transplant for treatment of high-risk hematologic disorders.

  • 2 views
  • 07 Mar, 2021
  • 1 location
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

This phase II trial studies how well an umbilical cord blood transplant with added sugar works with chemotherapy and radiation therapy in treating patients with leukemia or lymphoma. Giving

blood cell count
nucleated cells
residual disease
tacrolimus
residual tumor
  • 36 views
  • 30 Jan, 2021
  • 2 locations
Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases

RATIONALE: Umbilical cord blood transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy. PURPOSE: This phase II trial is studying how

umbilical cord blood transplantation
melphalan
antithymocyte globulin
fludarabine
prednisolone
  • 109 views
  • 07 Nov, 2020
  • 1 location
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM) Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective To test if treating people with SAA or MDS with a co-infusion of …

umbilical cord blood transplantation
filgrastim
immunosuppression
bone marrow transplant
hla-a
  • 12 views
  • 11 Feb, 2021
  • 1 location
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT BMT or PBSCT

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT, matched unrelated

  • 22 views
  • 25 Jan, 2021
  • 2 locations
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

have evidence of early demyelinating disease in the central nervous system (CNS) who are undergoing standard treatment with unrelated umbilical cord blood transplantation (UCBT). The secondary

umbilical cord blood transplantation
batten
adjunctive therapy
metachromatic leukodystrophy
demyelinating disease
  • 153 views
  • 28 Jan, 2021
  • 1 location