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Found 136 clinical trials
EUS-CPN With and Without Bupivacaine

Endoscopic ultrasound (EUS) allows EUS-guided trans gastric injection of absolute alcohol around the base of the celiac plexus (celiac plexus neurolysis (EUS-CPN)), to help alleviate pain associated with pancreatic cancer. It is standard procedure to inject bupivacaine immediately before injecting absolute alcohol, to theoretically prevent pain that may occur during …

endoscopic ultrasound
celiac
  • 0 views
  • 19 Nov, 2021
  • 1 location
Fascia Iliaca Compartment Block and PENG Block for Hip Arthroplasty

Hip arthroplasty is one of the most common orthopedic procedures especially in elderly patients due to deformation of joint. Patients may complain severe pain due to the surgical trauma and the prosthesis. Regional anesthesia methods may be performed to reduce opioid consumption and opioid-related side effects. The hip joint consists …

anesthesia
  • 0 views
  • 24 Mar, 2022
  • 1 location
Impact of 11-oxygenated Androgens on Metabolic Dysfunction of Women With Polycystic Ovary Syndrome (11OXO-PCOS)

Polycystic ovary syndrome (PCOS) affects 10% of all women and usually presents with irregular menstrual periods and difficulties conceiving. It is also a lifelong metabolic disorder and affected women have an increased risk of type 2 diabetes, high blood pressure, and heart disease. Increased blood levels of male hormones, also …

testosterone
dehydroepiandrosterone
androgens
diabetes
Accepts healthy volunteers
  • 0 views
  • 22 Mar, 2022
Magnetic Occult Lesion Localization Instrument (MOLLI) Guidance System for Breast Lesion Localization

The proposed trial is a non-randomized, multi-center, sequential arm registry evaluating clinical, and health economic outcomes following treatment with the Magnetic Occult Lesion Localization Instrument (MOLLI), an approved instrument for Breast Conserving Surgery (BCS) in patients with non-palpable lesions. All patients who have an area of concern in the breast …

mammogram
carcinoma
ductal carcinoma
breast-conserving surgery
  • 2 views
  • 05 Oct, 2021
  • 1 location
Study of BO-112 With Pembrolizumab for Colorectal or Gastric/GEJ Cancer With Liver Metastasis

This is an open, single arm, multicenter phase 2 trial in which BO-112 will be administered intratumorally in combination with intravenous pembrolizumab in patients with liver metastasis from colorectal, gastric or gastroesophageal junction cancers. The objective is to reverse the primary resistance that a subgroup of patients from these tumors …

erbb2
bevacizumab
fluoropyrimidine
cancer chemotherapy
oxaliplatin
  • 0 views
  • 27 Jan, 2021
  • 9 locations
Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral …

  • 0 views
  • 09 May, 2022
  • 1 location
A Comparison Between a PC and a CC Approach for the Placement of Infraclavicular Perineural Catheters in Hand Surgery

In outpatient hand surgery, 40% of patients report moderate to severe pain within 24 hours of the operation. Effective pain management is therefore essential to ensure a comfortable and safe return home for the patient. Loco-regional anesthesia is the optimal method of analgesia for complex hand surgery. It involves the …

pain relieving
anesthesia
nerve block
analgesia
bupivacaine
  • 0 views
  • 15 Jun, 2022
  • 1 location
Safety Distance for Endovenous Laser Ablation of the Great Saphenous Vein (SDEVLA)

Chronic venous disease is one of the most common diseases in the western world and worldwide with a prevalence of 83,6%. It is a chronic progressive disease, which causes a significant burden on health systems, treatment and care of these patients. Recurrence of varicose veins after successful treatment remains a …

  • 0 views
  • 06 Feb, 2022
Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy

This is a randomized, triple-masked, placebo-controlled parallel-arm human subjects clinical trial investigating the addition of a continuous erector spinae plane nerve block to a single-injection erector spinae plane block to provide postoperative analgesia following percutaneous nephrolithotomy. Participants will all receive a single-injection nerve block and perineural catheter insertion. Following surgery, …

  • 0 views
  • 08 Apr, 2022
  • 1 location
MRI Guided Transurethral HIFU for Various Prostate Diseases

This study assesses feasibility and safety, the primary outcomes, of MRI guided transurethral high intensity focused ultrasound (HIFU) ablation for prostate diseases (PD). We will enrol 10 patients to each group with criteria as follows: localised prostate cancer (PC); locally advanced PC; locally recurrent PC after external beam radiation therapy …

urinary symptoms
bladder outlet obstruction
anesthesia
hyperplasia
prostatectomy
  • 54 views
  • 16 May, 2021
  • 1 location