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Found 3 clinical trials
Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations

This BVD-523-ABC study builds on the safety and clinical activity experience of previous studies that have evaluated ulixertinib as a novel targeted cancer treatment in cohorts of patients with

  • 0 views
  • 26 May, 2022
  • 22 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

antineoplastic
glomerular filtration rate
graft versus host disease
alpha-fetoprotein
MRI
  • 1029 views
  • 27 May, 2022
  • 104 locations
Ulixertinib (BVD-523) and Hydroxychloroquine in Patients w Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas (UTAH)

Open-label dose escalation of Ulixertinib combined with fixed dose of hydroxychloroquine.

metastasis
neutrophil count
carcinoma
KRAS
absolute neutrophil count
  • 0 views
  • 13 Mar, 2022
  • 1 location