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Found 462 clinical trials
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis

Inflammatory bowel disease is a group of chronic, non-specific inflammatory diseases of the intestinal tract whose etiology has not yet been fully elucidated, including ulcerative colitis and

monoclonal antibodies
Accepts healthy volunteers
antibiotics
inflammatory bowel disease
crohn's disease
  • 0 views
  • 09 Aug, 2022
  • 1 location
The Impact of Circadian Misalignment on Colonic Barrier Homeostasis in Ulcerative Colitis

the inflammation of the gut. We hope to look at patients with Ulcerative Colitis and Healthy Controls.

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Long-term Safety and Efficacy Profile of ABX464 in Subjects With Moderate to Severe Active Ulcerative Colitis

This study is an open-label study aiming at evaluating the long-term safety and the efficacy profile of ABX464 given once a day (QD) at 25 mg in subjects who have been previously enrolled in the ABX464-102 or ABX464-104 studies (OLE and maintenance studies) and who are willing to continue their …

hematochezia
  • 0 views
  • 21 Mar, 2022
  • 3 locations
Characteristics of Anal Manometry Examination in Patients With Ulcerative Colitis (UC) in Remission With Anorectal Symptoms in a New Disease Compared to a Disease of Many Years

Inflammatory bowel diseases (IBD), which include Crohn's disease (CD) and ulcerative colitis (UC), are chronic immune-related diseases. IBD symptoms frequently overlap with symptoms of

remission
crohn's disease
loperamide
  • 0 views
  • 20 Aug, 2022
  • 1 location
Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Ulcerative Colitis

This is a pilot study of combination therapy using FMT and vedolizumab for induction of UC. The investigators hypothesize that a combination therapy approach which addresses immune trafficking

fecal microbiota transplantation
enemas
tumor necrosis factor
vedolizumab
microbiota
  • 0 views
  • 16 Sep, 2022
  • 1 location
A Phase 2/3, Multicenter, Randomized, Double-Blind Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Oral Ozanimod (RPC1063) in Pediatric Subjects With Moderately to Severely Active Ulcerative Colitis With an Inadequate Response to Conventional Therapy

participants with moderate to severe active ulcerative colitis (UC) who have had an inadequate response to conventional therapy.

remission
immunomodulators
endoscopy
aminosalicylates
corticosteroids
  • 0 views
  • 15 Sep, 2022
  • 2 locations
A Randomised Placebo-controlled Safety Study of Lactobacillus Reuteri BGP-014 in Patients With Mild to Moderate Ulcerative Colitis

The objectives of this study are to evaluate the safety, tolerability and preliminary efficacy of Lactobacillus reuteri BGP-014 in mild to moderate active Ulcerative Colitis (UC) patients as an

methotrexate
immunomodulators
azathioprine
mercaptopurine
hematochezia
  • 0 views
  • 18 Sep, 2022
  • 2 locations
A Multicenter, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of KBL697 in Patients With Mild to Moderate Active Ulcerative Colitis

The study is designed to investigate efficacy and safety of KBL697 in patients with mild to moderate active ulcerative colitis. KBL697 has been developed as a potential new treatment for

immunomodulators
corticosteroids
  • 0 views
  • 18 Sep, 2022
  • 1 location
  • 0 views
  • 23 Sep, 2022
  • 43 locations
Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management

The TRIUMPH study was designed to build on the existing literature by studying the efficacy of tofacitinib in hospitalized patients with acute severe ulcerative colitis. This trial will provide

  • 0 views
  • 24 Jun, 2021
  • 1 location