Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 462 clinical trials
Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative Colitis

statins in Bact2- enterotyped, healthy volunteers and ulcerative colitis patients. Evaluation of the effect of microbiota modulation on disease activity in ulcerative colitis patients.

remission
microbiota
  • 0 views
  • 21 May, 2021
  • 2 locations
Pharmacokinetics of Cobitolimod Enemas in Participants With Active Ulcerative Colitis

The purpose of the study is to evaluate the PK, safety and tolerability of cobitolimod ememas (500mg/50mL) given to participants with active left-sided UC.

endoscopy
enemas
hematochezia
  • 0 views
  • 29 Jun, 2022
  • 1 location
LFMT vs Placebo in New Biologic Start for Ulcerative Colitis

To compare the safety and efficacy of concomitant LFMT versus placebo in UC patients who are starting vedolizumab or ustekinumab.

vedolizumab
microbiota
  • 0 views
  • 28 Jul, 2022
  • 1 location
Diet Intervention as a Prebiotic Treatment for Active Ulcerative Colitis

The purpose of this study is to determine if a sustainable non-elemental diet can be used as a probiotic tool to alter the dysbiotic microbiome found in individuals with ulcerative colitis and

medical therapy
  • 0 views
  • 23 Sep, 2022
  • 1 location
Clinical Study of Cord Blood Mononuclear Cells on Treatment of Hormone-resistant or Hormone-dependent Ulcerative Colitis

This study conducted a systematic clinical observation of the clinical efficacy of UCB-MNCs in the treatment of hormone-resistant or hormone-dependent ulcerative colitis, in order to observe its

adalimumab
prednisone
azathioprine
  • 4 views
  • 22 May, 2021
  • 1 location
Assessment of Empagliflozin as Adjuvant Therapy in Patients With Ulcerative Colitis

treatment of mild to moderately active ulcerative colitis. Disease activity will be measured using Mayo score for ulcerative colitis activity. Calculation of the score requires patients to undergo

immunomodulators
  • 0 views
  • 11 Nov, 2021
  • 1 location
Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

The purpose of this Japan-only study is to assess the safety and efficacy of etrasimod at 2 doses in Japanese subjects with moderately to severely active ulcerative colitis (UC) when

endoscopy
  • 0 views
  • 17 Jun, 2022
  • 60 locations
  • 3 views
  • 20 Apr, 2022
  • 16 locations
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12

  • 0 views
  • 10 Aug, 2022
  • 1 location
CT to Assess the Efficacy and Safety of Adding GMA to Infliximab in Paediatric Patients With Steroid-refractory Ulcerative Colitis

The primary endpoint will be evaluated through the following variables: PUCAI score, IFX levels, and steroid treatment. Clinical response to IFX will be evaluated through the PUCAI score. The response will be considered clinically significant if PUCAI points continue maintained below 30 during the study period. The IFX response will …

corticosteroids
steroid therapy
infliximab
  • 0 views
  • 09 Jul, 2022
  • 7 locations