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Found 423 clinical trials
Cohort of Inflammatory Bowel Disease Patient in Yeouido St. Mary's Hospital

Pathologically Inflammatory bowel disease (IBD) is in chronic complex inflammatory gut pathological condition. Although the etiology of IBD is unknown, gut microbiota alteration (dysbiosis) is considered a novel factor involved in the pathogenesis of IBD. The aim of this study is to analyze gut microbiota in IBD patients.

enteropathy
microbiota
  • 0 views
  • 24 Mar, 2022
  • 1 location
Optimizing Outcomes for Older Veterans With Chronic Low Back Pain Syndrome: Aging Back Clinics

The purpose of this study is to compare two different ways to treat chronic low back pain. The two types of treatment that the investigators will compare are called Usual Care and ABC Care. Usual Care tends to focus on the spine. ABC Care focuses on the entire body and …

low back pain
Accepts healthy volunteers
  • 423 views
  • 19 Oct, 2022
  • 3 locations
VeDOlizumab PERsistence in IBD Patients After Switching From Intravenous to Subcutaneous Administration : a Real-life Multicenter Study (DOPER) (DOPER)

Descriptive : A 12-months multicenter, observational, prospective cohort study. Population : IBD patients under stable clinical and biological remission will be proposed to switch from the IV vedolizumab to the SC vedolizumab as part of routine care. All consecutive IBD patients in IBD centers participating in the study will be …

vedolizumab
mercaptopurine
azathioprine
remission
methotrexate
  • 0 views
  • 04 Oct, 2022
  • 1 location
Metabolic Responses to Bariatric Surgery

Research the genetic and biomechanical markers of human adipose tissue on patients with morbid obesity. Additional tissue/fluid collection is also gathered during the time of surgery.

diabetes
dyslipidemia
type 2 diabetes mellitus
bariatric surgery
  • 346 views
  • 26 Mar, 2022
  • 1 location
Understanding the Roles of Estradiol and Follicle-stimulating Hormone in Adipocyte Remodeling Following Surgical and Pharmacology-induced Menopause (RESUME-2 Study) (RESUME-2)

The overarching aims of this study are to: Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene and protein expression, in the scABD and scFEM depots of women undergoing surgical menopause (↓E2, ↑FSH). Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene …

fats
Accepts healthy volunteers
  • 0 views
  • 11 Oct, 2022
  • 1 location
Natural History of Intestinal Inflammation in People With Primary Immune Dysregulations

Background PIDD stands for primary immune dysregulation. It is a general term that includes many different inherited immune system disorders. The immune system is the part of the body that helps fight disease and infection. People with PIDDs can develop many kinds of health problems. One of these is inflammatory …

immunodeficiency
immune disorder
diarrhea
enteropathy
urine tests
  • 13 views
  • 04 Oct, 2022
  • 1 location
Assessment of Anorectal Function in Patients With Inflammatory Bowel Disease

Active inflammatory bowel disease (IBD) causes disabling symptoms such as diarrhea, involuntary loss of bowel control, abdominal pain and urges to pass stool. However, even patients with inactive IBD frequently experience such symptoms. The cause is not well understood and the functionality of the bowel in IBD patients is underexplored. …

anxiety
depression
enteropathy
Accepts healthy volunteers
abdominal pain
  • 0 views
  • 24 Mar, 2022
  • 1 location
Identification Genetic Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung Disease

To identify demographic, clinical, genetic, immunologic and/or microbial (i.e., fecal stream characterization) risk factors that influence the likelihood of development of the HAEC phenotype in children who carry the diagnosis of HD. The newly formed HAEC Collaborative Research Group (HCRG) will utilize the 4 participating centers in the current consortia …

  • 85 views
  • 21 Jan, 2021
  • 1 location
A 24-month Real Life PErsistence Efficacy and Safety Study in IBD Patients in REMission Switched From Intravenous Infliximab to Subcutaneous Infliximab CT-P13 Remsima®SC (PEREM)

Descriptive: A 24-month multicentre, observational, prospective cohort study. Population: IBD Patients under stable clinical and biological remission Study treatments: Patients who will be proposed to switch, or who have just switched, from the intravenous originator Remicade® or one of its biosimilars to the subcutaneous infliximab Remsima®SC as part of routine …

infliximab
biosimilar
azathioprine
remicade
remission
  • 0 views
  • 04 Oct, 2022
  • 1 location
NGS in Gallbladder Cancer and Response to Treatment

Evidence suggests distinct models of molecular and pathologic progression, and a growing body of genetics data points to a heterogeneous collection of underlying mutations in key oncogenes and tumor suppressor genes. Although tumor genetics have been used to tailor individual treatment regimens and guide clinical decision making in other cancers, …

cancer
  • 0 views
  • 18 Jun, 2022
  • 1 location