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Found 5 clinical trials
Sensation, Motion, and Quality of Life on Natalizumab and Off Natalizumab

The goal of this proposal is to use the BeCare App to (1) determine changes in "Feel Good Effect", or "Restoring Physiologic Homeostasis(RPH)"for individuals with relapsing-remitting MS (RRMS) before and after starting Natalizumab therapy and (2) Compare BeCare-derived with clinically-derived performance metrics.

natalizumab
tysabri
natalizumab therapy
  • 0 views
  • 09 Jan, 2022
  • 1 location
Natalizumab and Chronic Inflammation

In this study the investigators will assess the ability of Natalizumab, a medication given to treat multiple sclerosis (MS), to restore blood brain barrier integrity and repair subtle leakages of the blood brain barrier (BBB).

natalizumab
disease or disorder
  • 0 views
  • 25 Mar, 2022
  • 1 location
Hematopoietic Stem Cell Therapy for Inflammatory Multiple Sclerosis Failing Alternate Approved Therapy

The purpose of this study is to assess the efficacy of autologous PBSCT versus FDA approved standard of care (i.e. interferon, glatiramer acetate, mitoxantrone, natalizumab, fingolimod, or tecfidera) for inflammatory MS failing alternate approved therapy. Disease progression, defined as a 1-point increase in the Expanded Disability Status scale (EDSS) on …

copaxone
mitoxantrone
corticosteroids
tecfidera
rebif
  • 120 views
  • 08 Nov, 2020
  • 1 location
A Study for Tysabri Participant Preference

The primary objective of this study is to collect, evaluate and compare data on participant preference between subcutaneous (SC) and intravenous (IV) natalizumab. The secondary objectives of this study are to evaluate the immunogenicity of SC natalizumab for natalizumab-naïve participants and collect and evaluate data on the multiple sclerosis (MS) …

disease or disorder
natalizumab
tysabri
natalizumab therapy
  • 0 views
  • 25 Apr, 2022
  • 32 locations
Comparing the Safety and Benefit of Natalizumab (Tysabri®) At-home Infusion vs At-hospital Infusion in Multiple Sclerosis (Tys at Home)

At-home use of Natalizumab in multiple sclerosis (MS) patients has been temporarily granted by French security agency of medicines and Health products (ANSM). The main objective of the study is to compare the safety of natalizumab administration at home vs at hospital based on retrospective and prospective data collection. Quality …

MRI
natalizumab
tysabri
  • 0 views
  • 06 Apr, 2022
  • 18 locations