Found 2767 clinical trials
Hypertension Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)
The aim of this study is to determine if lowering blood pressure using FDA approved medication (antihypertensive drugs) alters brain pulsatility and reduces brain amyloid beta protein accumulation in older adults. Amyloid beta protein is high in the brain of older adults with Alzheimer's disease. Hypertension may increase brain amyloid …
- 98 views
- 21 Mar, 2022
- 1 location
Type 2 Diabetes Study – Seeking Volunteers Who Treat with Any Combination of Medications, Except Insulin.
We are currently seeking volunteers who are diagnosed with Type 2 Diabetes and who are treating with any combination of medications including any of the following:
- 129 views
- 08 Oct, 2021
- 1 location
A Prospective, Randomized, Double-masked, Sham-controlled, Multicenter, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NPDR)
This Phase 3 Study will evaluate the efficacy and safety of KSI-301 in participants with moderately severe to severe non-proliferative diabetic retinopathy (NPDR).
- 0 views
- 10 Mar, 2022
- 1 location
Diabetic Gastroparesis Study
Diabetic gastroparesis creates feelings of bloating, nausea, vomiting and pain. If you have diabetes, ClinSearch is enrolling volunteers in a study testing an investigational medication.
- 158 views
- 23 Mar, 2022
- 1 location
DIABETICS WITH FOOT ULCERS
A DIABETIC FOOT ULCER IS AN OPEN SORE OR WOUND THAT OCCURS IN APPROXIMATELY 15 PERCENT OF PATIENTS WITH DIABETES AND IS COMMONLY LOCATED ON THE BOTTOM OF THE FOOT.
- 100 views
- 11 Sep, 2019
- 1 location
Inflammatory Characterization of Known or Possible Cardiovascular Diseases
Background: Cardiometabolic diseases are a combination of medical disorders that, when they occur together, increase the risk of heart disease and diabetes
- 163 views
- 23 Nov, 2020
- 1 location
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative
diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. Another disorder, atherosclerosis, is a process in which cholesterol is gradually deposited
- 95 views
- 23 Nov, 2020
- 1 location
A Phase 2a, Double-blind, Randomized, Placebo-controlled, Proof of Concept Study of Vascular Endothelial Growth Factor (VEGF)-B Blockade with the Monoclonal Antibody CSL346 in Subjects with Diabetic Kidney Disease
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, proof of concept study to investigate the efficacy, safety, tolerability, and pharmacokinetics (PK) of repeat doses of CSL346 in 100 subjects with DKD and albuminuria receiving standard of care treatment.
- 22 views
- 12 Oct, 2021
- 1 location
Crest-2: CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) PROTOCOL
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …
- 0 views
- 08 Jan, 2022
- 1 location
Diabetes - Type 2 Diabetes Mellitus
Diabetes - Type 2 Diabetes Mellitus
- 75 views
- 08 Nov, 2020
- 1 location