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Found 141 clinical trials
Prolonged Air Leak (PAL) Autologous Blood Patch Intervention Trial

: To determine the safety and efficacy of autologous blood patch (ABP) as a means to reduce the rate of prolonged air leak (PAL) after lung cancer resection AIM 2: To prospectively examine

lung carcinoma
lung cancer
  • 19 Jul, 2021
  • 1 location
Chemotherapy and Maximal Tumor Debulking of Multi-organ Colorectal Cancer Metastases

treatment with combination chemotherapy or treatment with combination chemotherapy and additional maximal tumor debulking including surgical tumor resection, RFA, (DEBIRI-)TACE and SBRT, depending on best

  • 03 Jul, 2021
  • 30 locations
Resting-State Functional MRI in Glioma Patients Before and After Surgery

effects on language in patients with glioma. Mapping language function before brain tumor resection is crucial for preventing post-surgical deficits and maximizing restoration of language function

tumour resection
brain tumor
tumor resection
  • 09 Feb, 2022
  • 1 location
Prehabilitation in Esophageal Surgery (PRESS) (PRESS)

guidelines underline the possible role of prehabilitations' programs in reducing postoperative morbidity. In this trial, 200 patients, scheduled for esophageal cancer resection, will be randomly assigned to

  • 09 Feb, 2022
  • 1 location
FATLAS: Comprehensive Multi-level Characterization of Systemic and Mammary Adiposity in Breast Cancer Patients.

-Embedded (FFPE) samples from the tumour resection specimen and will consist of histological characterization, immuno assays, multiplex immunohistochemistry, DNA sequencing and single nuclei RNA sequencing

  • 26 Jan, 2021
  • 1 location
Neoadjuvant Irradiation of Extremity Soft Tissue Sarcoma With Ions

healing disorders from beginning of radiotherapy to maximum 120 days after the planned tumor resection or discontinuation of treatment due to any reason. The treatment is of shorter duration (2-3 weeks vs

soft tissue sarcoma
  • 09 Jul, 2021
  • 1 location
CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02)

) administrations following tumor resection and to establish a maximum tolerated dose (MTD) and a Recommended Phase 2a Dose (RP2D) for IV and IC CYNK-001 administration. For Phase IIa, to evaluate efficacy and

measurable disease
neutrophil count
karnofsky performance status
tumour resection
  • 17 Jun, 2022
  • 1 location
Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients. (SonoFIRST)

Glioblastoma (GBM) is an aggressive cancer with a progression-free survival (PFS) of 7 months and an overall survival (OS) of 15 months. Many therapeutic approaches have failed to improve the prognosis of patients to date. One of the main reasons is the presence of blood brain barrier (BBB) which limits …

  • 23 Apr, 2022
  • 3 locations
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

receptor (CAR) and EGFRt, delivered by an indwelling catheter in the tumor resection cavity or ventricular system in children and young adults with recurrent or refractory HER2-positive CNS tumors. A child

tumor resection
cns disease
cns neoplasm
  • 17 Mar, 2022
  • 1 location
Proton Therapy in the Treatment of Liver Metastases

, there is an important role for a treatment that can provide the equivalent of tumor resection with minimal morbidity. Stereotactic body radiotherapy (SBRT) delivers an ablative regimen of highly focused

stereotactic body radiotherapy
neutrophil count
stereotactic body radiation therapy
local therapy
pet/ct scan
  • 10 Mar, 2022
  • 1 location