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Found 140 clinical trials
Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma (DRI)

This study is being conducted to find out if the safety and tolerability of an experimental cell therapy is safe to administer to patients with a newly diagnosed glioblastoma multiforme (GBM) in combination with temozolomide (TMZ).

Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer (GABRINOX-ART)

The aim of this study is to demonstrate the efficacy of intensified and sequential chemotherapy (Gabrinox) comprising Gembrax regimen (Gemcitabine-Abraxane) followed by the Folfirinox regimen (5FU, Oxaliplatin and Irinotecan) in patients with locally advanced pancreatic adenocarcinoma. The study will also demonstrate the feasibility of combining this intensified chemotherapy with MRI-guided …

  • 0 views
  • 24 Mar, 2022
  • 5 locations
The Value of Palliative Primary Tumor Resection in Metastatic Colon Cancer

The aim of this trial is to evaluate the value of palliative primary tumor resection in colon cancer patients with initially unresectable metastases and a positive response to induction

metastasis
cancer
systemic chemotherapy
adenocarcinoma
adenocarcinoma of colon
  • 0 views
  • 24 Jan, 2021
  • 1 location
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection (ADAURA2)

This is a global study to assess the effects of osimertinib in participants with EGFRm stage IA2-IA3 non-small cell lung cancer following complete tumour resection.

lung carcinoma
EGFR
osimertinib
  • 0 views
  • 19 Jun, 2022
  • 31 locations
Surgery for Recurrent Glioblastoma (RESURGE)

-8 months. The strategy to repeat tumor resection at recurrence in order to minimize tumor load and thus to facilitate subsequent second-line therapy has been shown to be feasible and safe.

recurrent glioblastoma
temozolomide
tumour resection
MRI
  • 145 views
  • 27 May, 2022
  • 18 locations
Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over (ADAGE)

chemotherapy has demonstrated a benefit on disease-free survival and overall survival after a stage III colon cancer resection. Nevertheless adjuvant chemotherapy is poorly used in elderly patients. Prognostic

cancer
primary tumor
fluoropyrimidine
capecitabine
oxaliplatin
  • 31 views
  • 07 Apr, 2022
  • 137 locations
Intravenous Iron for Treatment of Anaemia Before Cardiac Surgery (ITACS)

This randomised double-blind, controlled phase IV trial will compare the efficacy, safety and cost-effectiveness of preoperative IV iron with placebo in patients with anaemia before elective cardiac surgery.

ferric carboxymaltose
iron
  • 227 views
  • 23 Feb, 2022
  • 1 location
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lorlatinib may stop the growth of tumor cells by blocking …

ganglioneuroblastoma
vincristine
isotretinoin
busulfan
stem cell transplantation
  • 117 views
  • 06 Jun, 2022
  • 95 locations
Indocyanine Green (ICG) Guided Tumor Resection

. Assess the sensitivity and specificity of NIR imagery for identifying residual disease at the conclusion of a tumor resection.

cancer
lymphoma
solid tumor
sarcoma
solid neoplasm
  • 0 views
  • 14 Apr, 2022
  • 1 location
Total Laparoscopic Versus Laparoscopic Assisted Left-sided Colon Cancer Resection

The comparison between total laparoscopic and laparoscopic assisted left hemicolon cancer resection underwent to choose a more effective and safe operation.

colectomy
hemicolectomy
  • 0 views
  • 26 Jan, 2021
  • 1 location