Found 141 clinical trials
Transanal Irrigation to Prevent Major Low Anterior Resection Syndrome (TAILARS)
Bowel dysfunction after rectal cancer resection comprises a vast array of bowel symptoms and associated quality-of-life impairment, collectively termed as low anterior resection syndrome (LARS
- 0 views
- 11 May, 2022
- 1 location
3D Printing for Pre-Surgical Planning (3D)
datasets to produce diagnostic 3D models with identical spatial/contrast resolution to the acquired datasets in the target areas of congenital cardiothoracic surgery, neurosurgical tumor resection and
- 0 views
- 24 Mar, 2022
- 2 locations
PREoperativ Study of Exercise Training (PRESET-RCT)
survival and quality of life. Exercise training is a promising strategy to improve physical functional before and after tumor resection, but it is not established if this translates into lower risk of peri
- 5 views
- 12 Feb, 2022
- 1 location
PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients
fibrosis of the head and neck: trismus and/or dysphagia Exclusion Criteria: History of primary cancer resection and/or reconstructive surgery to anatomical areas involved in
- 0 views
- 17 Oct, 2021
- 2 locations
General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial (GA-CARES)
This is a large pragmatic multicenter trial comparing maintenance of general anesthesia with total intravenous anesthesia using propofol versus volatile agent (sevoflurane, isoflurane, or desflurane) during cancer surgery. The primary endpoint is all-cause mortality.
- 8 views
- 24 Feb, 2022
- 5 locations
Manual Versus Targer-controll Infusion in Reduction of Awareness and Dreaming
This study compares manual total intravenous anesthesia (TIVA) and target-controll infusion (TCI) in reduction of awareness and dreaming, and the haemodynamical stability during operation. Half of patients will be anesthetized using manual TIVA and other half using TCI.
- 1 views
- 24 Mar, 2022
- 1 location
Inhibition of Oral Tumorigenesis by Antitumor B
This is a randomized, double-blinded, placebo-control window of opportunity study of Anti-tumor B versus placebo. Anti-tumor B is a botanical agent composed of six Chinese herbs: Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus brachyotus, Dictamnus dasycarpus, and Dioscorea bulbifera.
- 0 views
- 16 May, 2022
- 1 location
A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme
The current design provides a window to analyze the impact of the ACT001+Pembrolizumab combination on the tumor microenvironment and disease outcomes.
- 0 views
- 24 Nov, 2021
Feasibility of Individualized Therapy for Recurrent GBM
The current study will test the ability and likelihood of successfully implementing individualized combination treatment recommendations for adult patients with surgically-resectable recurrent glioblastoma in a timely fashion. Collected tumor tissue and blood will be examined using a new diagnostic testing called University of California, San Francisco (UCSF) 500 Cancer Gene …
- 13 views
- 01 Feb, 2022
- 1 location
The Role of Postoperative Cycles in the Perioperative Chemotherapy for Gastric Cancer (STOPEROPCHEM)
Taking into account the substantial doubts concerning the potential benefit of postoperative part in the perioperative chemotherapy regimen we designed a study assessing value of this approach in gastric cancer. To improve compliance with a protocol regimen of this aggressive combined therapy we replaced tested in the MAGIC trial ECF …
- 26 views
- 22 Jan, 2022
- 2 locations