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Found 195 clinical trials
Safety and Efficacy of Camrelizumab (Anti-PD-1 Antibody) in Recurrent HCC After Liver Transplantation

provides poor therapeutic effect, leading to tumor progression or intolerance. Before immunotherapy, the PD-L1 expression was confirmed negative in the graft liver by immunohistochemistry, and patients

immunohistochemistry
immune globulin
hepatocellular carcinoma
sorafenib
immunosuppression
  • 0 views
  • 15 May, 2022
  • 1 location
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

180 days. Risk assessment will include seizure, stroke, infection, tumor progression, and death.

MRI
blood transfusion
tumor progression
karnofsky performance status
glioblastoma multiforme
  • 20 views
  • 14 Jul, 2022
  • 1 location
An Open-Label Multi-Center Phase II Study of Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

antibody such as tocilizumab may inhibit cancer progression. Giving atezolizumab in combination with etrumadenant or tocilizumab may work better in treating prostate cancer.

testosterone
cancer
prostatectomy
testosterone level
tumor cells
  • 9 views
  • 27 Oct, 2022
  • 1 location
Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

, 2) allow for optimal chemotherapeutic dosing to achieve the greatest benefits and the least systemic side effects and 3) distinguish subsequent tumor progression from long-term MLA treatment effects

brain tumor
blood transfusion
recurrent tumor
tumor progression
g-csf
  • 35 views
  • 09 Jul, 2022
  • 1 location
Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases

, disease-free survival and quality of life for 5 years and compared to a "control group" of participants who drop out of study prior to transplantation due to reasons other than cancer progression.

liver metastasis
folfiri regimen
cancer
folfox regimen
bevacizumab
  • 206 views
  • 20 Apr, 2022
  • 1 location
Group Exercise Training for Fall Prevention and Functional Improvements During and After Treatment for Prostate Cancer

exposure and slow down cancer progression. While beneficial for cancer survival, significant treatment-induced side effects from ADT may lead to serious health consequences including falls, frailty, and

tumor progression
androgens
antiandrogen therapy
immunological adjuvant
androgen suppression
  • 3 views
  • 12 Oct, 2022
  • 1 location
A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancer (CHAMP)

ipilimumab. Subjects may continue receiving study drugs until cancer progression, severe toxicity, withdrawal of consent, 3 years from the initial dose of study drugs or study termination, whichever occurs

  • 8 views
  • 17 Jun, 2022
  • 1 location
A Study of RGX-202-01 as Combination Therapy in 2nd Line RAS Mutant Advanced Colorectal Cancer

inhibitor of the creatine transporter SLC6a8, a novel metabolic target that drives gastrointestinal cancer progression. During the dose escalation stage, multiple doses of orally administered RGX-202

oxaliplatin
tumor cells
metastasis
immunohistochemistry
diabetes mellitus
  • 310 views
  • 04 Oct, 2022
  • 5 locations
Phase II Trial of Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory Glioblastoma Multiforme, Anaplastic Astrocytoma, and Anaplastic Oligoastrocytoma

prevent tumor progression in patients with recurrent, residual GBM.

monoclonal antibodies
growth factor
tumor progression
glioblastoma multiforme
tyrosine
  • 283 views
  • 28 Oct, 2022
  • 1 location
A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

explore the effects of each drug on the immune system. Undergo scans every 6 weeks to test the effect of treatment on cancer progression. Undergo other study procedures to evaluate drug

  • 0 views
  • 11 Apr, 2023
  • 3 locations