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Found 86 clinical trials
Early Detection of Prostate Cancer (PROLIPSY)

classic peripheral tumour markers, such as Prostate Health Index (PHI) and PCA3. Follow up evaluations will be initiated to assess the prognostic relevance of the candidate biomarkers determined in this

  • 0 views
  • 25 Mar, 2022
Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation

study are Independent imaging and tumor markers assess ORR (objective response rate) in patients with recurrent and metastatic ovarian cancer and endometrial cancer with P53 mutation treated with

metastasis
tumor markers
measurable disease
stage iv ovarian epithelial cancer
cancer
  • 1 views
  • 25 Jan, 2021
  • 1 location
Personalized Precision Diagnosis and Treatment of Pancreatic Cancer (PPDTPC)

particularly poor prognosis due to the late onset of symptoms and the advanced stage that the disease usually reaches before diagnosis. Therefore, searching more sensitive and accurate tumor markers has great

metastasis
tumor markers
cancer chemotherapy
antineoplastic
  • 0 views
  • 05 Mar, 2022
  • 1 location
A Single Arm Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR)

This is a single arm, open-label, lead in phase Ib dose confirmation, followed by phase II study with 2 parallel study cohorts. Patients will be pre-screened for presence of 1q21.3 copy number amplification in plasma samples prior to screening process. Only patients with confirmed plasma cell-free DNA (cfDNA) 1q21.3 copy …

metastasis
cancer treatment
immunostimulant
  • 0 views
  • 25 Jan, 2021
  • 1 location
Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer (GRECCAR15)

GRECCAR 15 is focused on Locally Recurrent Rectal Cancer (LRRC) for patients with previous pelvic radiotherapy for the primary rectal cancer. This situation leads to a 20% higher risk of non-curative resection for the LRRC management (R1 status) impacting significantly the overall survival. The widespread use of neoadjuvant radiotherapy for …

metastasis
renal function
irinotecan
capecitabine
oxaliplatin
  • 0 views
  • 14 Feb, 2022
  • 15 locations
Clinical Study of Granulocyte Infusion for Advanced Cancer

Background & Rationale: For years, most tumor immunotherapy researches have focused on T cell and natural killer (NK) cell therapies, most of which involve amplification and modification of the patient's immune cells for reinfusion therapy. However, for the treatment of solid tumors, there is currently little breakthrough. Recently, researchers have …

ct scan
metastasis
measurable disease
solid neoplasm
renal function
  • 0 views
  • 23 Jan, 2021
  • 1 location
Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17) (GRECCAR17)

GRECCAR 17 will be the first prospective and randomized trial to assess a tailored policy in the use of defunctioning stoma after TME according to the personalized risk of anastomotic leakage. The tailored use of defunctioning stoma after TME for rectal cancer should improve both the quality of life of …

  • 0 views
  • 20 Apr, 2022
Added Value in Combined Use of Fusion Imaging and Contrast-enhanced Ultrasonography

So far, there have been studies showing that the CEUS-grafted technique has added value in biopsy and RFA, but no studies have compared the group using only fusion and the group using CEUS+fusion. Therefore, the additional added value of CEUS will be evaluated by comparing the two groups.

  • 0 views
  • 18 Apr, 2021
  • 1 location
Clinical Evaluation of a New Form of Cancer Therapy (Atavistic Chemotherapy) Based on the Principles of Atavistic Metamorphosis (2011)

The cell behavior that the investigators regard as "malignant," including: cell autonomy; invasion and digestion of surrounding normal tissues; migration and colonization of distant organs; ability to develop resistance to drugs, temperature, or radiation; and ability to kill the host, are not only characteristics of cancer cells, but of pathogenic …

metastasis
tumor markers
combinations
cancer treatment
primary cancer
  • 30 views
  • 26 Apr, 2022
  • 1 location
Re-irradiation With Stereotactic Body Radiotherapy for Relapsed Pancreatic Cancer

The safety and efficacy of re-irradiation with stereotactic body radiotherapy for relapsed pancreatic cancer will be evaluated.

recurrent pancreatic cancer
stereotactic body radiation therapy
neutrophil count
  • 0 views
  • 24 Mar, 2022
  • 1 location