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Found 174 clinical trials
Individualized Fortification of Human Milk for Infants Born ≤ 1250 g (MaxiMoM-InForM)

. At 4 months CA, growth and body composition will be determined by air displacement plethysmography and processing speed by electroencephalography on a subset of infants. Neurodevelopment will be

  • 19 Apr, 2022
Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer

neoadjuvant chemotherapy. The sooner the systemic chemotherapy is received, the better suppression it has on activity of tumor growth factors. Pre-operative chemotherapy may eliminate tiny metastases. It may

  • 25 Feb, 2022
  • 1 location
Effect of Mirabegron on Promoting Brown Adipose Tissue Activation

In previous preclinical studies, our group found that Mirabegron, a clinical drug, could activate brown adipose tissue and inhibit tumor growth in tumour-bearing mice.Investigators look forward

Accepts healthy volunteers
  • 07 Apr, 2023
  • 1 location
Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

This phase II trial compares the effect of adding triapine to lutetium Lu 177 dotatate versus lutetium Lu 177 dotatate alone (standard therapy) in shrinking tumors or slowing tumor growth in

  • 16 Sep, 2023
  • 3 locations
A Safety Lead-In/Randomized Phase 2 Study of BMX-001 as a Therapeutic Agent for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy

(MBM) undergoing whole brain radiation therapy (WBRT). Preliminary studies have demonstrated that BMX-001 provides protection of normal tissues from radiation-induced injury and augments tumor growth

  • 18 Oct, 2022
  • 4 locations
A Phase 1b Trial Investigating Docetaxel Combined With Cirmtuzumab in Patients With Metastatic Castration Resistant Prostate Cancer

the non-canonical Wnt pathway and is suspected to contribute to prostate cancer growth and progression.

  • 20 Oct, 2022
  • 1 location
Olaparib for PAH: a Multicenter Clinical Trial (OPTION)

can reverse PAH in several animal models1. Interestingly, PARP1 inhibition is also cardioprotective. Olaparib, an orally available PARP1 inhibitor, can reverse cancer growth in animals and humans with

serum pregnancy test
pulmonary disease
body mass index
  • 09 Jun, 2022
  • 3 locations
Study of Biomarkers in Gynecological Cancers

. Further research is needed to better understand the changes found in cancer cells and how to target them to stop or reduce cancer growth. A drug that may be able to block certain specific cancer

cancer care
  • 26 Feb, 2022
  • 1 location
Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

lungs. These bacterial changes may aid tumor growth. Researchers want to find out if treating the bacteria, too, can help cancer treatment work better. Objective

  • 23 Sep, 2023
  • 1 location
Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction

DOX cardiotoxicity, enhances survival and enhances the effects of DOX on cancer growth in a rat breast cancer model. The investigators suspect that SFN affects DOX metabolism in cancer cells to

  • 15 Aug, 2023
  • 1 location