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Found 1703 clinical trials
Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG)

antitumor-specific immunity after radiation induced immunological tumor cell death (ICD). With radiation, tumor cells release tumor antigens that are captured by antigen presenting dendritic cells. Immune

  • 0 views
  • 29 Nov, 2021
  • 1 location
TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC) (TACE-Ax-HCQ)

therapy such as TACE has a higher response rate and improves progression-free survival (PFS), but the benefit is still limited. Cancer cells escape ischemic cell death via autophagy and hypoxia-inducible

  • 0 views
  • 11 May, 2022
  • 1 location
Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed Classical Hodgkin Lymphoma

monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in a targeted way and delivers vedotin to kill them. Nivolumab is an antibody that

  • 0 views
  • 25 Mar, 2022
  • 1 location
Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma

radiation therapy that sends x-rays directly to the tumor using smaller doses over several days and may cause less damage to normal tissue. Aflibercept may stop the growth of tumor cells by blocking some of

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

have had or will require surgery to remove cancer cells prior to starting chemoradiation may be enrolled. All eligible patients will receive de-intensified cisplatin-based chemoradiation, with high

  • 0 views
  • 04 Oct, 2022
  • 3 locations
68Ga-PSMA PET Imaging of Upper Metastatic Gastric Cancers to Determine Eligibility to Endoradiotherapy (ERD2021)

protocols). These options are not applicable to all patients and may have significant toxicities. Endoradiotherapy (ERT) using a radioisotope coupled with a localization vector specifically targeting tumor

  • 0 views
  • 21 Mar, 2022
Rituximab + High-Dose Methylprednisolone Debulking Prior to Venetoclax for CLL & SLL Patients

The purpose of the study is to investigate whether the combination of rituximab and high dose methylprednisolone can be given together, can reduce the amount of cancer cells that are present

  • 0 views
  • 14 Apr, 2022
  • 1 location
SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

blood that is directed against your cancer cells. This study also aims to determine whether treatment with SurVaxM plus temozolomide improves the survival of glioblastoma patients like yourself compared

  • 21 views
  • 07 Oct, 2022
  • 10 locations
A Phase I Trial of Cancer-targeting Micelles for Non-myoinvasive Bladder Cancer

that contain the chemotherapy drug paclitaxel. PLZ4 is a molecule that can possibly guide PPM to specifically target and deliver paclitaxel into and kill bladder cancer cells. In this trial, PPM will

  • 0 views
  • 27 Oct, 2022
  • 1 location
Safety and Pharmacokinetics of REGN2810 (Cemiplimab) Anti-programmed Death-ligand 1 (Anti-PD-1) in Japanese Adult Patients With Advanced Malignancies

treatment of Japanese patients with advanced squamous or non-squamous non-small cell lung cancer (NSCLC) whose tumors express programmed cell death ligand 1 (PD-L1) in ≥50% of tumor cells (PD-L1^hi). (Part

ipilimumab
  • 15 views
  • 07 Oct, 2022
  • 20 locations