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Found 1710 clinical trials
  • 0 views
  • 27 Oct, 2022
  • 2 locations
A Phase I Study to Assess Safety of Selective JAK 1 Inhibitor, Itacitinib, in Patients With Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplant (HCT)

This phase I trial studies how well itacitinib works for the treatment of bronchiolitis obliterans syndrome after donor hematopoietic cell transplant. Itacitinib may stop the growth of tumor

  • 0 views
  • 22 Oct, 2022
  • 1 location
Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC

may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.

  • 2 views
  • 07 Oct, 2022
  • 1 location
sEphB4-HSA in Treating Patients With Kaposi Sarcoma

that provide blood to the cancer, and may also prevent cancer cells from growing.

  • 0 views
  • 09 Jul, 2022
  • 9 locations
First in Human Phase 1 Study of AOH1996 in Patients With Refractory Solid Tumors

This phase I trial studies the side effects and best dose of AOH1996 in treating patients with solid tumors that do not respond to treatment (refractory). AOH1996 may stop the growth of tumor

  • 0 views
  • 20 Oct, 2022
  • 1 location
GE-148-002: A Phase 2 Open-label Single-Center Study to Assess GE-148 (18F) Injection PET Imaging to Detect Localized Prostate Cancer

Background: - GE-148 (18F) is a new drug that is designed to attach to prostate cancer cells. Researchers are interested in combining the drug with a small amount of radioactive material

  • 36 views
  • 08 Nov, 2020
  • 1 location
Everolimus in Treating Patients With Recurrent or Progressive Low-Grade Glioma

RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is

  • 24 views
  • 07 Nov, 2020
  • 1 location
Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.

tumor cells
metastasis
  • 10 views
  • 16 Mar, 2022
  • 1 location
Tamoxifen in Treating Patients With Metastatic Bladder Cancer That Did Not Respond to Previous Chemotherapy

RATIONALE: Tamoxifen may slow the growth of tumor cells and may be an effective treatment for patients with metastatic bladder cancer that did not respond to previous chemotherapy

tumor cells
  • 35 views
  • 07 Nov, 2020
  • 1 location
A Phase 1 Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of Thorium-227 Labeled Antibody-chelator Conjugate BAY2701439, in Participants With Advanced HER2-expressing Tumors

drug is a type of therapy called a 'targeted alpha therapy' which uses an antibody to deliver a radioactive particle to cancer cells. BAY2701439 contains thorium-227 which emits radiation (a lot of

  • 2 views
  • 14 Oct, 2022
  • 6 locations