Found 1710 clinical trials
A Multicenter Phase II Study of Pomalidomide Monotherapy in Kaposi Sarcoma
immune system, and may kill cancer cells.
- 0 views
- 27 Oct, 2022
- 2 locations
A Phase I Study to Assess Safety of Selective JAK 1 Inhibitor, Itacitinib, in Patients With Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplant (HCT)
This phase I trial studies how well itacitinib works for the treatment of bronchiolitis obliterans syndrome after donor hematopoietic cell transplant. Itacitinib may stop the growth of tumor
- 0 views
- 22 Oct, 2022
- 1 location
Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCC
may selectively target Epidermolysis bullosa (EB) cancer cells while leaving normal EB cells unaffected.
- 2 views
- 07 Oct, 2022
- 1 location
sEphB4-HSA in Treating Patients With Kaposi Sarcoma
that provide blood to the cancer, and may also prevent cancer cells from growing.
- 0 views
- 09 Jul, 2022
- 9 locations
First in Human Phase 1 Study of AOH1996 in Patients With Refractory Solid Tumors
This phase I trial studies the side effects and best dose of AOH1996 in treating patients with solid tumors that do not respond to treatment (refractory). AOH1996 may stop the growth of tumor
- 0 views
- 20 Oct, 2022
- 1 location
GE-148-002: A Phase 2 Open-label Single-Center Study to Assess GE-148 (18F) Injection PET Imaging to Detect Localized Prostate Cancer
Background: - GE-148 (18F) is a new drug that is designed to attach to prostate cancer cells. Researchers are interested in combining the drug with a small amount of radioactive material
- 36 views
- 08 Nov, 2020
- 1 location
Everolimus in Treating Patients With Recurrent or Progressive Low-Grade Glioma
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: This phase II trial is
- 24 views
- 07 Nov, 2020
- 1 location
Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort
higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.
- 10 views
- 16 Mar, 2022
- 1 location
Tamoxifen in Treating Patients With Metastatic Bladder Cancer That Did Not Respond to Previous Chemotherapy
RATIONALE: Tamoxifen may slow the growth of tumor cells and may be an effective treatment for patients with metastatic bladder cancer that did not respond to previous chemotherapy
- 35 views
- 07 Nov, 2020
- 1 location
A Phase 1 Open-label, First-in-human, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of Thorium-227 Labeled Antibody-chelator Conjugate BAY2701439, in Participants With Advanced HER2-expressing Tumors
drug is a type of therapy called a 'targeted alpha therapy' which uses an antibody to deliver a radioactive particle to cancer cells. BAY2701439 contains thorium-227 which emits radiation (a lot of
- 2 views
- 14 Oct, 2022
- 6 locations