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Found 123 clinical trials
Comparison of Intermittent Androgen Deprivation Therapy With or Without Irradiation Recovery in Prostate Cancer Patients (OLIGOPELVIS2)

Metastatic prostate cancer has traditionally been regarded as an incurable dissemination of disease, and treatment is focused on delaying progression rather than eliminating all tumor burden

androgens
prostatectomy
prostate cancer metastatic
antiandrogen therapy
serum testosterone
  • 1 views
  • 07 Feb, 2022
  • 9 locations
Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases (LIVERT(W)OHEAL)

chemotherapy. Patients are excluded from the study if there is an extrahepatic tumor burden (with the exception of resectable lung metastases) or if the patient is not suitable for liver transplantation due to

pulmonary metastasis
carcinoma
combination therapy
hepatectomy
systemic chemotherapy
  • 31 views
  • 24 Apr, 2022
  • 2 locations
Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative (LENVABLA)

these situations, around 20%. Difficult-to-access tumors can furthermore be treated by percutaneous irreversible electrotroporation (IRE). Despite a tumor burden accessible for curative ablation

measurable disease
platelet count
renal function
neutrophil count
cancer
  • 0 views
  • 23 Apr, 2022
Study Assessing Stereotactic Radiotherapy in Therapeutic Strategy of Oligoprogressive Renal Cell Carcinoma Metastases

emergence of resistant tumor clonal cells, some patients progress only on few sites while the rest of tumor burden is controlled. In this setting named oligoprogressive disease [isolated progression of &lt

rapamycin
tyrosine
ct scan
kidney cancer
systemic therapy
  • 0 views
  • 13 Apr, 2021
  • 17 locations
Comparison Between High-dose Amoxicillin Dual Therapy and Pylera Quadruple Therapy in the Treatment of Helicobacter Pylori Infection

eradication constitutes an essential Public Health measurement, being inclusively considered a cost-effective method to decrease the gastric cancer burden, by promoting pre-malignant lesions regression, such

Accepts healthy volunteers
gastric adenocarcinoma
antibiotics
adenocarcinoma
endoscopy
  • 0 views
  • 07 Nov, 2021
  • 1 location
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc) (Stereosarc)

provided that tumor burden remains limited in the number and size of metastases. Systemic treatment can be combined with SBRT. SBRT may produce abscopal effects where tumors outside the irradiation area

liposarcoma
ipilimumab
tumor cells
leiomyosarcoma
immunomodulators
  • 0 views
  • 10 Aug, 2022
  • 1 location
Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies

The purpose of this study is to evaluate the safety and tolerability of BGB-11417 monotherapy, define the maximum tolerated dose (MTD) or maximum administered dose and the recommended Phase 2 dose (RP2D) of BGB-11417 monotherapy for the selected B-cell malignancy dose finding cohorts, and evaluate the safety and tolerability of …

  • 0 views
  • 11 Aug, 2021
  • 1 location
Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma

The purpose of this study is to test the safety and effectiveness of immunotherapy (checkpoint inhibitor therapy) in advanced bladder cancer when given intermittently. An unanswered question with the use of CPI (checkpoint inhibitor) is the duration of therapy required for optimal clinical benefit. In the absence of progressive disease …

atezolizumab
measurable disease
bladder cancer
avelumab
gilbert's syndrome
  • 0 views
  • 16 Jun, 2022
  • 1 location
Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer (APRE)

The investigators are conducting this study with men that have prostate cancer and are getting standard of care treatment with the drugs abiraterone acetate and prednisone. The study will follow men with prostate cancer from initiation of participation in the study and for up to 10 years. The reason for …

androgens
bicalutamide
abiraterone
docetaxel
metastasis
  • 0 views
  • 25 Jul, 2022
  • 2 locations
CapTemY90 for Grade 2 NET Liver Metastases (CapTemY90)

This is a Phase 2 evaluation of hepatic-progression free survival among patients with Grade 2 liver-dominant NET metastases undergoing combination therapy with CapTem and Y90 radioembolization.The hypothesis is to confirm safety and to assess if disease control is improved relative to expectation from either therapy alone.

  • 0 views
  • 05 Jun, 2022
  • 3 locations